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Tumor Dormancy, Quiescence, and Senescence, Vol. 3: Aging, Cancer, and Noncancer Pathologies (Tumor Dormancy and Cellular Quiescence and Senescence) - Hardcover
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THIS THIRD VOLUME IN THE SERIES TUMOR DORMANCY, QUIESCENCE, AND SENESCENCE DISCUSSES THE ROLE OF TUMOR DORMANCY AND SENESCENCE IN A NUMBER OF DISEASES, INCLUDING BREAST CANCER, OVARIAN CANCER AND LEUKEMIA. THE CONTENTS ARE ORGANIZED UNDER FIVE SUBHEADINGS: GENERAL APPLICATIONS, ROLE IN BREAST CANCER, ROLE IN OVARIAN CANCER, ROLE IN LEUKEMIA AND ROLE IN CARDIOVASCULAR DISEASE. THE FIRST SECTION INCLUDES BASIC INFORMATION ON THE DEFINITION OF DORMANCY, HOW CELLS BECOME SENESCENT AND WHAT THEY DO, ALONG WITH AN APPRAISAL OF THE CURRENT STATE OF RESEARCH ON DORMANCY. SECTION TWO EXPLORES DORMANCY IN BREAST CANCER, INCLUDING THE PROGRESSION OF HORMONE-DEPENDENT MAMMARY TUMORS AFTER DORMANCY. SECTION THREE DETAILS THE RESISTANCE OF TYPE II OVARIAN TUMORS, IN WHICH THE RESISTANT TUMOR CELL POPULATION PERSISTS AFTER CHEMOTHERAPY IN A STATE OF DORMANCY, WITH RECURRENT TUMORS ARISING UPON TRANSFORMATION OF SUCH DORMANT CELLS BACK TO MALIGNANT GROWTH. THIS SECTION EXPLAINS HOW LINEAGE, HISTOLOGICAL SUBTYPES AND GRADE INFLUENCE THE DIFFERENTIAL RESPONSE OF OVARIAN CANCER RESISTANCE TO PLATINUM DRUGS. THE FOURTH SECTION EXPLORES LEUKEMIA, DISCUSSING REGULATION OF THE PROMYELOCYTIC LEUKEMIA PROTEIN AND ITS ROLE IN PREMATURE SENESCENCE. THE FINAL SECTION EXPLORES THE ROLE OF SENESCENCE AND AUTOPHAGY IN AGE-RELATED CARDIOVASCULAR DISEASES AND THE OBSERVATION THAT AUTOPHAGY SEEMS TO RETARD CARDIAC SENESCENCE. LIKE THE TWO PRECEDING VOLUMES IN THE SERIES, VOLUME 3 STANDS OUT FOR ITS COMPREHENSIVE APPROACH, ITS ROSTER OF SOME 26 EXPERT CONTRIBUTORS REPRESENTING SEVEN DIFFERENT COUNTRIES AND ITS UP-TO-DATE REVIEW OF LEADING-EDGE TECHNOLOGY AND METHODS.
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This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods.
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- VerlagSpringer
- Erscheinungsdatum2014
- ISBN 10 9401793247
- ISBN 13 9789401793247
- EinbandTapa dura
- Anzahl der Seiten172
- HerausgeberHayat M. A.
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3: Aging, Cancer, and Noncancer Pathologies (Tumor Dormancy and Cellular Quiescence and Senescence) [Hardcover ]
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3: Aging, Cancer, and Noncancer Pathologies (Tumor Dormancy and Cellular Quiescence and Senescence, 3)
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Tumor Dormancy, Quiescence, and Senescence : Aging, Cancer, and Noncancer Pathologies
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3: Aging, Cancer, and Noncancer Pathologies
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3
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Springer Netherlands Sep 2014
(2014)
ISBN 10: 9401793247
ISBN 13: 9789401793247
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Buchbeschreibung Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods. 172 pp. Englisch. Bestandsnummer des Verkäufers 9789401793247
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3
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ISBN 13: 9789401793247
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Buchbeschreibung Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Discusses the effects of senescence and dormancy in breast cancer, ovarian cancer and leukemia, as well as in cardiovascular diseases Advances the body of knowledge of cancer cell regression, including possible use of pro senescence therapy as an . Bestandsnummer des Verkäufers 5838140
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3 : Aging, Cancer, and Noncancer Pathologies
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Springer Netherlands
(2014)
ISBN 10: 9401793247
ISBN 13: 9789401793247
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Buchbeschreibung Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This third volume in the series Tumor Dormancy, Quiescence, and Senescence discusses the role of tumor dormancy and senescence in a number of diseases, including breast cancer, ovarian cancer and leukemia. The contents are organized under five subheadings: General Applications, Role in Breast Cancer, Role in Ovarian Cancer, Role in Leukemia and Role in Cardiovascular Disease. The first section includes basic information on the definition of dormancy, how cells become senescent and what they do, along with an appraisal of the current state of research on dormancy. Section Two explores dormancy in breast cancer, including the progression of hormone-dependent mammary tumors after dormancy. Section Three details the resistance of Type II ovarian tumors, in which the resistant tumor cell population persists after chemotherapy in a state of dormancy, with recurrent tumors arising upon transformation of such dormant cells back to malignant growth. This section explains how lineage, histological subtypes and grade influence the differential response of ovarian cancer resistance to platinum drugs. The fourth section explores leukemia, discussing regulation of the promyelocytic leukemia protein and its role in premature senescence. The final section explores the role of senescence and autophagy in age-related cardiovascular diseases and the observation that autophagy seems to retard cardiac senescence. Like the two preceding volumes in the series, Volume 3 stands out for its comprehensive approach, its roster of some 26 expert contributors representing seven different countries and its up-to-date review of leading-edge technology and methods. Bestandsnummer des Verkäufers 9789401793247
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Buchbeschreibung Hardcover. Zustand: Brand New. 1st edition. 144 pages. 10.25x7.25x0.75 inches. In Stock. Bestandsnummer des Verkäufers x-9401793247
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3
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Buchbeschreibung Zustand: New. Tumor Dormancy, Quiescence, and Senescence, Vol. 3 Editor(s): Hayat, M. A. Series: Tumor Dormancy and Cellular Quiescence and Senescence. Num Pages: 170 pages, 19 colour illustrations, 2 black & white tables, biography. BIC Classification: MBGR; PSA. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 11. Weight in Grams: 529. . 2014. Hardback. . . . . Bestandsnummer des Verkäufers V9789401793247
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Tumor Dormancy, Quiescence, and Senescence, Vol. 3
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Buchbeschreibung Zustand: New. Tumor Dormancy, Quiescence, and Senescence, Vol. 3 Editor(s): Hayat, M. A. Series: Tumor Dormancy and Cellular Quiescence and Senescence. Num Pages: 170 pages, 19 colour illustrations, 2 black & white tables, biography. BIC Classification: MBGR; PSA. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 11. Weight in Grams: 529. . 2014. Hardback. . . . . Books ship from the US and Ireland. Bestandsnummer des Verkäufers V9789401793247
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