Discovery of Small-Molecule Modulators of Protein-RNA Interactions for Treating Cancer and COVID-19 - Softcover

Wan Gi Byun

Softcover

ISBN 10: 9811978158 ISBN 13: 9789811978159

Verlag: Springer Nature B.V., 2022

Inhaltsangabe

This book describes the development of novel protein-RNA-binding assays and their applications in a high-throughput manner for the identification of small-molecule modulators of protein-RNA interactions to treat cancer and COVID-19.Modulating protein-RNA interactions with small molecules is expected to provide novel biological insights of the interrelation of diseases with the protein-RNA interactome. The modulations may also be exploited therapeutically. For these reasons, the development of a simple, reliable, and sensitive protein-RNA-binding assay is necessary for high-throughput screening to discover new effective chemical entities capable of acting on diverse protein-RNA interactions. This book discusses the discovery of small-molecule modulators targeting protein-RNA interactions that are potentially valuable to treat cancer and COVID-19 by constructing novel high-throughput screening methods. The results of this dissertation provide valuable insights into the regulation of protein-RNA interactions in chemical biology and drug development.

Details zur Ausgabe

• Verlag: Springer Nature B.V.
• Erscheinungsdatum: 2022
• Sprache: Englisch
• ISBN 10: 9811978158
• ISBN 13: 9789811978159
• Einband: Tapa blanda
• Anzahl der Seiten: 162
• Kontakt zum Hersteller: Nicht verfügbar
• Verantwortliche Person: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Deutschland