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Therapy With Cultured Cells - Softcover

Green, Howard

 
9789814267700: Therapy With Cultured Cells

Inhaltsangabe

In this book the author describes the discoveries in his laboratory that led to therapy with cultured cells. The first cultured cell type used for therapy was the keratinocyte of the epidermis, for the treatment of burns. Subsequent developments led to the use of cultured cells for the treatment of diseases of the eye, of the joints and of other diseases. Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries, as well as in France, Sweden and Greece, for the treatment of disease.

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Über die Autorinnen und Autoren

Dr. Green received his Doctorate in Medicine at the University of Toronto. He began his independent scientific work at New York University School of Medicine, where he ultimately became Professor and Chairman of the Department of Cell Biology. From 1970-1980 he was Professor of Cell Biology at Massachusetts Institute of Technology. He came to Harvard Medical School in 1980 and served as Chairman of the Department of Cellular and Molecular Physiology from then until 1993. Since then he has been George Higginson Professor in the Department of Cell Biology. While at MIT and Harvard Medical School, he developed the first therapeutic use of cultured cells - the use of keratinocytes for the regeneration of epidermis on severely burned patients. The first large-scale, life-saving use of this procedure was demonstrated with cells grown in his laboratory on the 6th floor of Building C2, where his lab is still located.



Howard Green was born and spent his early years in Canada. In 1947, he graduated from the Faculty of Medicine at the University of Toronto. Shortly after, he moved to the United States, where he has lived ever since. He has been a professor at New York University School of Medicine (1965 -1970), at the Massachusetts Institute of Technology (1970 -1980) and from 1980 to the present time at Harvard Medical School, where he is a member of the Department of Cell Biology. In recent years, his research has been on the properties of human embryonic stem cells and their derivatives. Dr. Green is a member of the National Academy of Sciences of the USA and a foreign member of the French Academy of Sciences. He has received numerous awards and honorary doctorates in the United States and abroad. Most recently he received the French Legion of Honor and the Blaise Pascal Medal of the European Academy of Sciences.

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The author described in this book the discoveries in his laboratory that led to therapy with cultured cells. The first cultured cell type used for therapy was the keratinocyte of the epidermis, for the treatment of burns. Subsequent developments led to the use of cultured cells for the treatment of diseases of the eye, of the joints and for other diseases. Cultured cells for therapy are now being prepared by industries in the US, Japan and Korea and are used in the aforesaid countries as well as France, Sweden and Greece, for the treatment of disease. In addition to keratinocytes, therapeutic use has been made of many cultured cell types, such as ocular limbal cells, chondrocytes and melanocytes. In addition to these cell types, which must be autologous, use has also been made of allogeneic keratinocytes to promote healing.

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