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Therapeutic RNA Nanotechnology: Immunomodulation and Dynamicity - Hardcover

 
9789814877183: Therapeutic RNA Nanotechnology: Immunomodulation and Dynamicity
Hardcover
ISBN 10: 9814877182 ISBN 13: 9789814877183
Verlag: Jenny Stanford Publishing, 2021

Inhaltsangabe

This collection of research articles and reviews covers the latest work in the design, delivery, dynamic abilities, and immune stimulation of RNA nanoparticles which have driven the utilization of their immunomodulatory properties. The unknown immune properties of nucleic acid nanoparticles have been a major hurdle in their adaptation until the works herein began assessing their structure-activity relationships. This collection chronologically follows the path of investigating the recognition of design components to implementing them into nucleic acid nanostructures. 

RNA nanotechnology is an emerging platform for therapeutics with increasing clinical relevance as this approach becomes more widely used and approved for the treatment of various diseases. The latest research aims to take advantage of RNA’s modular nature for the design of nanostructures which can interact with their environments to communicate programmed messages with intracellular pathways. In doing so, nanoparticles can be used to elicit or elude responses by the immune system as desired in conjunction with their therapeutic applications. 

 

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Über die Autorin bzw. den Autor

Kirill Afonin graduated from Saint Petersburg State University, followed by Ph.D. from Bowling Green State University, earned under supervision of Dr. Neocles Leontis. He then completed a Postdoctoral Fellowship in Chemistry and Biochemistry in the lab of Dr. Luc Jaeger at the University of California Santa Barbara and was invited to join the group of Dr. Bruce Shapiro at the National Cancer Institute, NIH, where Dr. Afonin established and managed an experimental branch within the Computational RNA Structure Group. He now serves as an Associate Professor at the University of North Carolina at Charlotte in the Department of Chemistry. 

Morgan Chandler received her B.S. in Biological Sciences with Honors from the University of North Carolina at Charlotte. She is currently a Ph.D. student in the Nanoscale Science Program at the University of North Carolina at Charlotte, where she works in the laboratory of Dr. Kirill Afonin in the Department of Chemistry.

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Verlag
Jenny Stanford Publishing
Erscheinungsdatum
2021
Sprache
Englisch
ISBN 10 
9814877182
ISBN 13 
9789814877183
Einband
Gebundene Ausgabe
Anzahl der Seiten
1180
Herausgeber
Afonin Kirill A., Chandler Morgan
Kontakt zum Hersteller
Taylor & Francis
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