Acetylsalicylic Acid (Aspirin): Impacts of Acetylsalicylic acid on histopathological parameter of female Albino rat, Rattus norvegicus

Jain, Neha; Raghuwanshi, Arun K.; Shrivastava, Vinoy K.

ISBN 10: 3659200735 / ISBN 13: 9783659200731

Verlag: LAP LAMBERT Academic Publishing, 2012

In. Bestandsnummer des Verkäufers ria9783659200731_new

Inhaltsangabe:

Aspirin (acetylsalicylic acid, ASA) has been used as one of the most famous, cheap, easily available and widely used Non Steroidal Anti Inflammatory Drug (NSAID). Aspirin is used in versatile purpose such as, anti-inflammatory (in joint diseases), anti-platelets (in cardiovascular disease), analgesic and antipyretic. The aim of present investigation is to study the effect of oral administration of drug acetylsalicylic acid (ASA, aspirin) on female albino rat, Rattus norvegicus. The female rats (n=24) were allocated into 2 groups as control (n=12) and treated (n=12). The treated rats were given oral dose of aspirin 100 mg/ kg body weight for 15 days (n=6) and 30 days (n=6). The present investigation results suggest that the high doses of ASA, induced histopathological changes in liver, kidney and reproductive organs directly or indirectly through modulation of certain biochemical and enzymological activities. These effects are dose and duration dependent.

Über die Autorin bzw. den Autor: M.Sc., M.Phil., Research Scholar,Laboratory of Endocrinology,Department of Biosciences,Barkatullah University,Bhopal-462026, Madhya Pradesh,INDIA

Bibliografische Details

Titel: Acetylsalicylic Acid (Aspirin): Impacts of ...
Verlag: LAP LAMBERT Academic Publishing
Erscheinungsdatum: 2012
Einband: Softcover
Zustand: New