Titel: Adaptive Design Theory and Implementation Using SAS and R (Chapman & Hall/CRC Biostatistics Series)
Verlag: Chapman and Hall/CRC
Erscheinungsjahr: 2007
Sprache: Englisch
ISBN-10: 1584889624
ISBN-13: 9781584889625
Einband: Hardcover
Zustand: As New
Zustand des Schutzumschlags: No Jacket

�ber diesen Titel

Inhaltsangabe

Adaptive design has become an important tool in modern pharmaceutical research and development. Compared to a classic trial design with static features, an adaptive design allows for the modification of the characteristics of ongoing trials based on cumulative information. Adaptive designs increase the probability of success, reduce costs and the time to market, and promote accurate drug delivery to patients.
Reflecting the state of the art in adaptive design approaches, Adaptive Design Theory and Implementation Using SAS and R provides a concise, unified presentation of adaptive design theories, uses SAS and R for the design and simulation of adaptive trials, and illustrates how to master different adaptive designs through real-world examples. The book focuses on simple two-stage adaptive designs with sample size re-estimation before moving on to explore more challenging designs and issues that include drop-loser, adaptive dose-funding, biomarker-adaptive, multiple-endpoint adaptive, response-adaptive randomization, and Bayesian adaptive designs. In many of the chapters, the author compares methods and provides practical examples of the designs, including those used in oncology, cardiovascular, and inflammation trials.
Equipped with the knowledge of adaptive design presented in this book, you will be able to improve the efficiency of your trial design, thereby reducing the time and cost of drug development.

�ber die Autorin bzw. den Autor

Millennium Pharmaceuticals, Cambridge, Massachusetts, USA

��ber diesen Titel� kann sich auf eine andere Ausgabe dieses Titels beziehen.

Anbieterinformationen

ThriftBooks is a fully independent seller of used books, having sold more than 160 million used and new books since we started in 2003. Each quality used book is sorted, graded, shelved and shipped by hand by our team of dedicated employees in our seven warehouses across the US. We have the best selection of books, in the right condition and format, at everyday low prices. We also have a dedicated, US-based Customer Service team, ranked in the top three by Newsweek for Best Customer Service in 2018 and 2019, so you can shop with confidence. We support and invest in our employees, appreciate and value our customers, and truly believe in the power of the written word to educate, energize, and engage readers of all ages and interests.

Zur Homepage des Verk�ufers

Unternehmensdaten des Verk�ufers

Thrift Books Global, LLC
18300 Cascade Ave S, Ste 150, Seattle, WA, 98188, U.S.A.

Gesch�ftsbedingungen und Versandinformationen

Verkaufsbedingungen

We guarantee the condition of every book as it's described
on the Abebooks website. If you're dissatisfied with your
purchase (Incorrect Book/Not as Described/Damaged) or if the
order hasn't arrived, you're eligible for a refund within 30
days of the estimated delivery date. If you've changed your
mind about a book that you've ordered, please use the "Ask
bookseller a question link to contact us" and we'll respond
as soon as possible.

Versandbedingungen

All domestic Standard and Expedited shipments are distributed from our warehouses by OSM, then handed off to the USPS for final delivery.

2-Day Shipping is delivered by FedEx, which does not deliver to PO boxes.

International shipments are tendered to the local postal service in the destination country for final delivery – we do not use courier services for international deliveries.