Base Editors: Methods and Protocols

Sangsu Bae

ISBN 10: 107162881X / ISBN 13: 9781071628812

Verlag: Springer-Verlag New York Inc., 2024

Beschreibung

This item is printed on demand. New copy - Usually dispatched within 5-9 working days 478.

Bestandsnummer des Verkäufers C9781071628812

Bibliografische Details

• Titel: Base Editors: Methods and Protocols
• Verlag: Springer-Verlag New York Inc.
• Erscheinungsjahr: 2024
• Sprache: Englisch
• ISBN-10: 107162881X
• ISBN-13: 9781071628812
• Einband: Paperback / softback
• Zustand: New

Über diesen Titel

Inhaltsangabe

This volume explores base editors (BEs), an invaluable CRISPR-based genome editing tool with a wide variety of versatile applications. Beginning with an overview of BEs, their diverse variants, and computational tools, the book continues with experimental applications of BEs for disease modeling in mammalian cells and generating mutagenic mice, therapeutic base editing strategies, which covers delivery methods of BE-encoded DNA plasmids, mRNAs, or ribonucleoproteins through viruses or non-viral lipid nanoparticles, and lastly, the use of BEs in plants and bacteria. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 

Authoritative and practical, Base Editors: Methods and Protocols serves as an ideal guide for researchers looking to use base editors to continue their studies in an array of fields.