In biology, signal transduction is the transmission of information into and within the cell. Signal transduction events within a cell are often initiated from an extracellular cue. Current knowledge suggests that there are far fewer intracellular second messengers than extracellular cues. This means that a conserved core set of second messengers, including ions, small nucleotides, and lipids must be coordinated to pass the information from their point of origin to their audience receptors effectively. In many cases, signal transduction involves significant amplification. One of the best-understood and ubiquitous second messengers is ionic calcium (Ca2+). The knowledge surrounding the coding of information via Ca2+ signals has served as a template for studying other second messengers. Ca2+ signaling and intracellular Ca2+ homeostasis are highly complex and still incompletely understood. In this chapter, will we review the current knowledge of Ca2+ signaling. We will first provide a review of the general principles of Ca2+ signal transduction and examples of some of the major Ca2+-dependent cellular processes. Next, we will review the main sources of Ca2+ and the molecular effectors of Ca2+ signals. Then, we will provide some examples from the literature that illustrate how Ca2+ signaling works: how it can mediate signal amplification, how it encodes different types of signals, how it performs agonist-specific signals as well as function-specific signals, signal integration and co-incidence detection, and how it can cross-talk with other second messenger signaling events. Throughout this chapter, we will use Ca2+ as an example of a prototypical coded second messenger, since it is clear that much of the complexity of Ca2+ signaling likely applies to many of the other known second messengers.

Table of Contents: General Introduction / Sources of Ca2+ Signals / Ca2+-Dependent Processes: From Highly Specialized to Ubiquitous Cellular Roles / Major Ca2+-Signaling Effectors / Ca2+ Signal Coding / Acknowledgments / Bibliography / Titles of Related Interest

�ber die Autorin bzw. den Autor:

Department of Cellular and Physiological Sciences, University of British Columbia

��ber diesen Titel� kann sich auf eine andere Ausgabe dieses Titels beziehen.

Anbieterinformationen

Quality books, speedy shipping, and great customer service! Please note that used items may not include access codes or cards, CD's or other accessories, regardless of what is stated in item title. If you need to guarantee that these items are included, please purchase a brand new copy.

Zur Homepage des Verk�ufers

Unternehmensdaten des Verk�ufers

J2B Holdings, LLC
13770 NOEL RD, #803600, Dallas, TX, 75240, U.S.A.

Gesch�ftsbedingungen:

We guarantee the condition of every book as it's described on the AbeBooks web
sites. Please note that used items may not include access codes or cards, CD's
or other accessories, regardless of what is stated in item title. If you need to
guarantee that these items are included, please purchase a brand new copy.

All requests for refunds and/or returns will be processed in accordance with
AbeBooks policies. If you're dissatisfied with your purchase (Incorrect Book/Not
as Described/Damaged) or if ...

Mehr Information

Versandinformationen:

Books ordered via expedited shipping should arrive between 2 and 7 business days after shipment confirmation. Books ordered via standard shipping should arrive between 4 and 14 business days after shipment confirmation.

Zahlungsarten
akzeptiert von diesem Verk�ufer

Zu Kaufgesuchen hinzuf�gen

Verwandte Artikel zu Ca2+-dependent Signal Transduction (Colloquium Building...

Ca2+-dependent Signal Transduction (Colloquium Building Blocks of the Cell: Cell Structure and Function)

Johnson, James D.; Bround, Michael J.; Albrecht, Tobias

Neu - Softcover

Unternehmensdaten des Verk�ufers