The Dynamic Neuron

Smythies John R Smythies John

ISBN 10: 0262194732 / ISBN 13: 9780262194730

Verlag: The MIT Press Bookstore, 2002

Beschreibung

pp. viii + 150 Illus.

Bestandsnummer des Verkäufers 7415490

Bibliografische Details

• Titel: The Dynamic Neuron
• Verlag: The MIT Press Bookstore
• Erscheinungsjahr: 2002
• Sprache: Englisch
• ISBN-10: 0262194732
• ISBN-13: 9780262194730
• Einband: Hardcover
• Zustand: New

Über diesen Titel

Inhaltsangabe

A comprehensive review of current research on synaptic plasticity.

The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity.

The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease.

Über die Autorin bzw. den Autor

John Smythies was Professor Emeritus of Psychology at the University of California, San Diego, and at the Neurology Institute in London with appointments at Harvard and at the University of Washington, Seattle. He is one of the pre-eminent researchers who studies the neurochemistry of schizophrenia and mental illness.