Formulation And Evaluation of Metformin and Glimepiride: Sustained Release Metformin And Immidiate Release Glimepiride

Sahdev, Anil Kumar; Gupta, Khushboo

ISBN 10: 3659781312 / ISBN 13: 9783659781315

Verlag: LAP LAMBERT Academic Publishing, 2017

Beschreibung

Print on Demand.

Bestandsnummer des Verkäufers 409981481

Bibliografische Details

• Titel: Formulation And Evaluation of Metformin and Glimepiride: Sustained Release Metformin And Immidiate Release Glimepiride
• Verlag: LAP LAMBERT Academic Publishing
• Erscheinungsjahr: 2017
• Sprache: Englisch
• ISBN-10: 3659781312
• ISBN-13: 9783659781315
• Einband: Softcover
• Zustand: New

Über diesen Titel

Inhaltsangabe

The objective of this research was to develop a combined anti-diabetic formulation of two different drugs acting by different mechanism. So they can complement each other and together lower the blood glucose level effectively. Metformin and glimepiride act by different mechanisms. Glimepiride reduce hyper glycaemia by enhancing insulin secretion, whereas metformin acts to improve insulin sensitivity and suppress hepatic glucose output. Because of their complementary mechanism of action, combination therapy with glimepiride and metformin would be rational and may lead to benefits in terms of improved glycaemic control and improved tolerability at lower doses of the individual agents.Sustained drug delivery can improve patient compliance and help in maintaining effective level of blood glucose.

Über die Autorin bzw. den Autor

Anil Kumar Sahdev*( Assistant Professor) and Khushboo Gupta (M.Pharma), Innovative college of pharmacy Greater noida (Uttar Pradesh), India.