HPLC METHOD DEVELOPMENT - A Step-by-Step Practical Guide for Every Analyte Type (Paperback)

Sprache: Englisch

Verlag: Independently Published, 2026

9798183822632

Serie: Buch 7 von 15 - Practical Pharma Science™ - Applied Knowledge for Pharma Professionals

Anbieter: Grand Eagle Retail, Bensenville, IL, USAGrand Eagle Retail

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Verkäufer:in bei AbeBooks seit 12. Oktober 2005

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Artikelbeschreibung des Verkäufers

Paperback. Method development is not about random experimentation, it is a decision tree. If you get the order right, the method nearly builds itself. HPLC Method Development -A Step-by-Step Practical Guide for Every Analyte Type takes you from the desk to a fully validated method, providing a clear, no-fluff protocol for every analyte class you will encounter in the pharmaceutical industry.Whether you are struggling with a complex mixture, a tailing basic compound, or a challenging peptide, this guide provides the levers that matter.Why This Book is Essential for Your LabHighly Illustrated & Decision-Driven: Move away from trial-and-error. Learn to use the Universal Decision Matrix to define your mode, column, and starting pH before you ever touch the instrument.Bench-Ready Protocols: Every chapter offers a step-by-step protocol tailored to specific analyte classes: Non-Polar, Polar, Acid, Base, Zwitterion, Chiral, Peptide, and Oligonucleotide.Master Design of Experiments (DoE): Don't just guess, map your success. Includes two complete, hands-on chapters on DoE, showing you how to find the global optimum and define a robust Method Operable Design Region (MODR) that satisfies modern regulatory expectations.Troubleshooting Detective Stories: Learn to recognize symptoms instantly. From "Everything elutes at the void" to "Peak splitting," each troubleshooting section provides the likely cause and the first fix to get you back on track immediately.Real-World Case Studies: Learn from 10 practical appendices that walk you through complete molecules, taking them from a problematic sample to a fully validated, regulatory-ready method.What's Inside: The Analyte Toolkit: Master the two numbers that run everything, log P (retention) and pKa (pH control).The "Grand" Decision Tree: Learn the four-step logic (Size Chirality Polarity Charge) that guarantees you select the correct mode every time.Critical Pair Focus: Learn to name your "critical pair" during scouting so every subsequent optimization decision targets the exact separation you need.Regulatory Compliance: Packed with ICH Q14-aligned guidance, helping you build methods that are robust by design, not by luck.Who Should Read This?This book is the definitive desk reference for analytical chemists, QC scientists, and pharmaceutical researchers who need to produce robust, reproducible, and compliant HPLC methods efficiently.Stop wasting time in the lab. Learn the decision logic that turns complex problems into validated solutions. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Bestandsnummer des Verkäufers 9798183822632

Titel
HPLC METHOD DEVELOPMENT - A Step-by-Step Practical Guide for Every Analyte Type (Paperback)
Autor
Mirela Gorjanu
Verlag
Independently Published
Erscheinungsjahr
2026
Zustand
new
Einband
Paperback
Sprache
Englisch
ISBN-13
9798183822632
Serie
Buch 7 von 15: Practical Pharma Science™ - Applied Knowledge for Pharma Professionals

Grand Eagle Retail

Bensenville, IL, USA

Verkäufer/-in mit 5 Sternen

Verkäufer:in bei AbeBooks seit 12. Oktober 2005

Versandkosten innerhalb von USA

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