The Herg Cardiac Potassium Channel: Structure, Function and Drug-Induced Long Qt Syndrome

Goode, J

ISBN 10: 0470021403 / ISBN 13: 9780470021408

Verlag: John Wiley and Sons, 2005

This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,700grams, ISBN:9780470021408. Bestandsnummer des Verkäufers 5574241

Inhaltsangabe:

This book draws together contributions from basic, pharmaceutical and clinical sciences aimed at a better understanding of the structure and function of hERG and the molecular basis for compound binding.
 
It features regulatory authority perspectives on preferred preclinical test systems and includes topics on hERG channel gating, regulation of functional expression, pharmacological properties of hERG/IKr channels, drug-induced long QT syndrome and preclinical evaluation and regulatory recommendations for assessing QT prolongation risks.
 
Better understanding of the role of the hERG channel in drug-induced cardiac arrhythmias should ultimately lead to the development of important, new and safer medicines.

Über die Autorin bzw. den Autor: The Novartis Foundation is an international scientific and educational charity that promotes the study and general knowledge of science and in particular encourages international co-operation in scientific research.

Bibliografische Details

Titel: The Herg Cardiac Potassium Channel: ...
Verlag: John Wiley and Sons
Erscheinungsdatum: 2005
Einband: Hardcover
Zustand: Good