The Inflammasomes (Progress in Inflammation Research)

ISBN 10: 3034803435 ISBN 13: 9783034803434

Verlag: Springer, 2013

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The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

Von der hinteren Coverseite: The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.

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Titel: The Inflammasomes (Progress in Inflammation ...
Verlag: Springer
Erscheinungsdatum: 2013
Einband: Softcover
Zustand: New

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The Inflammasomes

Couillin, Isabelle|P�trilli, Virginie|Martinon, Fabio

Verlag: Springer Basel, 2013

ISBN 10: 3034803435 ISBN 13: 9783034803434

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Overview on the current knowledge of inflammasome biologyHighlights the role of inflammasomes in health and diseaseWith contributions by leading international expertsThe inflammasome was first described in 2002 as a molecular comple. Bestandsnummer des Verk�ufers 4318212

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The Inflammasomes

Isabelle Couillin (u. a.)

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ISBN 10: 3034803435 ISBN 13: 9783034803434

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The Inflammasomes (Progress in Inflammation Research)

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ISBN 10: 3034803435 ISBN 13: 9783034803434

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The Inflammasomes

Isabelle Couillin

Verlag: Springer Basel, 2013

ISBN 10: 3034803435 ISBN 13: 9783034803434

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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease. Bestandsnummer des Verk�ufers 9783034803434

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The Inflammasomes

Isabelle Couillin

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ISBN 10: 3034803435 ISBN 13: 9783034803434

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Taschenbuch. Zustand: Neu. Neuware -The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1� and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 240 pp. Englisch. Bestandsnummer des Verk�ufers 9783034803434

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The Inflammasomes

Isabelle Couillin

Verlag: Springer Basel Nov 2013, 2013

ISBN 10: 3034803435 ISBN 13: 9783034803434

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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions of leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology and their role in health and disease. 240 pp. Englisch. Bestandsnummer des Verk�ufers 9783034803434

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