Innovative DNA Array Technology Detection of Pharmaceuticals Reclaimed Water (Paperback)

Sprache: Englisch

Verlag: IWA Publishing, London, 2007

1843397374 / 9781843397373

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Paperback. Numerous pharmaceutical substances and their metabolites have been identified in the aquatic environment. Due to their unique environmental fate and lack of appropriate biomonitoring techniques, the potential risk of these compounds to public and environmental health has largely been undetermined. Recent interest in quantifying pharmaceuticals in waste effluents and aquatic environments has identified the need to develop bioanalytical assays that will accurately reflect presence of these compounds. The goal of this research was to investigate the use of DNA microarrays as a bioanalytical tool for analysis of pharmaceutical contamination in re-use waters. Results from this study suggest that prototypic pharmaceutical contaminants target molecular events associated with pharmaceutical-induced gene induction and repression in exposed organisms. Gene expression profiles are subsequently evaluated as a means to discern pharmaceutical exposure. When fully developed, this bioanalytical approach will provide an efficient and robust method for screening pharmaceutical contaminants in reuse and other water matrices. Numerous pharmaceutical substances and their metabolites have been identified in the aquatic environment. Due to their unique environmental fate and lack of appropriate biomonitoring techniques, the potential risk of these compounds to public and environmental health has largely been undetermined. Recent interest in quantifying pharmaceuticals in waste effluents and aquatic environments has identified the need to develop bioanalytical assays that will accurately reflect presence of these compounds. The goal of this research was to investigate the use of DNA microarrays as a bioanalytical tool for analysis of pharmaceutical contamination in re-use waters. Results from this study suggest that prototypic pharmaceutical contaminants target molecular events associated with pharmaceutical-induced gene induction and repression in exposed organisms. Gene expression profiles are subsequently evaluated as a means to discern pharmaceutical exposure. When fully developed, this bioanalytical approach will provide an efficient and robust method for screening pharmaceutical contaminants in reuse and other water matrices. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Bestandsnummer des Verkäufers 9781843397373

Titel
Innovative DNA Array Technology Detection of Pharmaceuticals Reclaimed Water (Paperback)
Autor
S.W. Kullman
Verlag
IWA Publishing, London
Veröffentlichungsjahr
2007
Zustand
new
Einband
Paperback
Sprache
Englisch
ISBN-10
1843397374
ISBN-13
9781843397373

Grand Eagle Retail

Bensenville, IL, USA

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AbeBooks-Verkäufer/-in seit 12. Oktober 2005

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