Manipulation of Mammalian Development

Ralph B. L. Gwatkin

ISBN 10: 1461292654 / ISBN 13: 9781461292654

Verlag: Springer, 2012

Manipulation of Mammalian Development | Ralph B. L. Gwatkin | Taschenbuch | Developmental Biology | xiv | Englisch | 2012 | Springer | EAN 9781461292654 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. Bestandsnummer des Verkäufers 105322769

Inhaltsangabe:

Developmental biology has been transformed recently by discoveries in the fields of molecular biology, cell biology, and immunology. New ways of manip­ ulating mammalian development are uncovering control mechanisms and ena­ bling us to apply them in solving practical problems in animal production and human health. This book outlines some of these new manipulations and how they have contributed to the present state of developmental biology. Chapter 1 describes gene transfer by micro injection of cloned recombinant DNA into zygotes. Although the factors that affect transformation frequencies and integration sites are still unknown, such techniques offer a number of exciting prospects. Research models for human disease coula be artificially created and desirable characteristics in agricultural animals could be - hanced. . The theme of cell-to-cell transfer is continued in Chapters 2 and 3. Chapter 2 describes pronuclear transplantation by Sendai virus-induced fusion of the karyoplast with the enucleated embryo. Using this procedure, it has been dem­ onstrated that both male and female genomes are essential for normal develop­ ment, although the reason for this is not yet understood. Chapter 3 describes studies on the fusion of whole oocytes. .

Bibliografische Details

Titel: Manipulation of Mammalian Development
Verlag: Springer
Erscheinungsdatum: 2012
Einband: Taschenbuch
Zustand: Neu