Medical Applications of Finite Mixture Models

Peter Schlattmann

ISBN 10: 3540686509 / ISBN 13: 9783540686507

Verlag: Springer-Verlag GmbH, 2009

Beschreibung

Zustand: Gut | Seiten: 246 | Sprache: Englisch | Produktart: Bücher.

Bestandsnummer des Verkäufers 4449450/13

Bibliografische Details

• Titel: Medical Applications of Finite Mixture Models
• Verlag: Springer-Verlag GmbH
• Erscheinungsjahr: 2009
• Sprache: Englisch
• ISBN-10: 3540686509
• ISBN-13: 9783540686507
• Einband: Hardcover
• Zustand: Gut

Über diesen Titel

Inhaltsangabe

Patients are not alike! This simple truth is often ignored in the analysis of me- cal data, since most of the time results are presented for the "average" patient. As a result, potential variability between patients is ignored when presenting, e.g., the results of a multiple linear regression model. In medicine there are more and more attempts to individualize therapy; thus, from the author's point of view biostatis- cians should support these efforts. Therefore, one of the tasks of the statistician is to identify heterogeneity of patients and, if possible, to explain part of it with known explanatory covariates. Finite mixture models may be used to aid this purpose. This book tries to show that there are a large range of applications. They include the analysis of gene - pression data, pharmacokinetics, toxicology, and the determinants of beta-carotene plasma levels. Other examples include disease clustering, data from psychophysi- ogy, and meta-analysis of published studies. The book is intended as a resource for those interested in applying these methods.

Über die Autorin bzw. den Autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.