Method Development And Validations For Antimalarial Drugs: A Strategy Of Method Development And Validations For Antimalarial In Formulations

Lawal, Almustapha; Umar, Rabiu A.; Abubakar, Muazu G.; Lawal, Almustapha; Umar, Rabiu A.; Abubakar, Mu'azu G.

ISBN 10: 3659201820 / ISBN 13: 9783659201820

Verlag: Lap Lambert Academic Publishing, 2012

132 pages. 8.66x5.91x0.30 inches. In Stock. Bestandsnummer des Verkäufers 3659201820

Inhaltsangabe:

Substandard and counterfeit pharmaceutical, especially antimalarials, is a well-recognized and growing public health problem. According to WHO there have been an alarming number of reports of counterfeit antimalarials throughout the world and insufficient regulations and high demand of these very costly pharmaceuticals continues to fuel counterfeiting activity especially in the developing countries. Considering the WHO definition of a counterfeit medicine, in addition, to inadequate resources which mean that there is a scarcity of sophisticated analytical techniques, which hampers the ability to distinguish between genuine and counterfeit drugs. In line with these problems, methods were developed and validated using a reverse phase HPLC method with variable wavelength detector (VWD) for quantification of amodiaquine (AMQ), chloroquine (CQ) and artesunate (ATS) in formulations and spectrophotometric methods using methylene blue and soluble starch as chromogenic agents for Artesunate.

Bibliografische Details

Titel: Method Development And Validations For ...
Verlag: Lap Lambert Academic Publishing
Erscheinungsdatum: 2012
Einband: Paperback
Zustand: Brand New