Microbial biofilm control strategies: Understanding and controlling microbial biofilm formation by surface engineering and novel biofilm inhibitors

Hou, Shuyu

ISBN 10: 3843357277 / ISBN 13: 9783843357272

Verlag: LAP LAMBERT Academic Publishing, 2010

Beschreibung

Gut/Very good: Buch bzw. Schutzumschlag mit wenigen Gebrauchsspuren an Einband, Schutzumschlag oder Seiten. / Describes a book or dust jacket that does show some signs of wear on either the binding, dust jacket or pages. Bestandsnummer des Verkäufers M03843357277-V

Bibliografische Details

Titel: Microbial biofilm control strategies: ...

Verlag: LAP LAMBERT Academic Publishing

Erscheinungsdatum: 2010

Einband: Softcover

Zustand: very good

Über diesen Titel

Inhaltsangabe:

Biofilms cause serious problems including biocorrosion and biofouling in industrial environment and persistent infections in clinical setting. As one of key intrinsic mechanisms, biofilms aggravate the wide spread of drug resistance. Despite significant problems caused by biofilms, effective biofilm control remains challenging. In this work, several interdisciplinary approaches were developed and characterized to better understand the fundamentals of biofilm formation and to improve biofilm control. Self-assembled monolayers (SAMs) were applied to obtain well-defined surfaces with tunable inertness to microbial adhesion and biofilm formation by changing the functional groups. It allows studying microbe-surface interactions at the molecular and cellular levels. Several approaches were also explored to better control biofilms, including brominated furanones and antimicrobial peptides as novel biofilm inhibitors, and biocompatible hydrogels embedding silver as efficient antimicrobial biomaterial. These studies provide new insights for understanding biofilm formation and developing biofilm control with enhanced prolonged efficacy.