Mitochondrial DNA : Methods and Protocols

Thomas J. Nicholls

ISBN 10: 1071629212 / ISBN 13: 9781071629215

Verlag: Springer US, Springer US, 2023

Beschreibung

Druck auf Anfrage Neuware - Printed after ordering - This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover invitroandin vivomethods,including for mtDNAisolation, visualization, deep sequencing, gene editing, and diagnostic aspects of mtDNA disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.Authoritative and cutting-edge,Mitochondrial DNA: Methods and Protocols aims to be useful and informative for researchers and clinicians with an interest in mitochondrial DNA.

Bestandsnummer des Verkäufers 9781071629215

Bibliografische Details

• Titel: Mitochondrial DNA : Methods and Protocols
• Verlag: Springer US, Springer US
• Erscheinungsjahr: 2023
• Sprache: Englisch
• ISBN-10: 1071629212
• ISBN-13: 9781071629215
• Einband: Buch
• Zustand: Neu

Über diesen Titel

Inhaltsangabe

This volume compiles a comprehensive range of methods to study key aspects of mitochondrial DNA including nucleoid structure and packaging, replication, genome integrity, and disease. Chapters are organized into eight methodological sections that cover in vitro and in vivo methods, including for mtDNA isolation, visualization, deep sequencing,  gene editing, and diagnostic aspects of mtDNA disease. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and methods, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.

Authoritative and cutting-edge, Mitochondrial DNA: Methods and Protocols aims to be useful and informative for researchers and clinicians with an interest in mitochondrial DNA.