Molecular Aspects of Innate and Adaptive Immunity

Sprache: Englisch

Verlag: Royal Society of Chemistry, GB, 2008

0854046984 / 9780854046980

Anbieter: Rarewaves USA United, HEBRON, KY, USARarewaves USA United

Verkäufer/-in mit 5 Sternen

AbeBooks-Verkäufer/-in seit 20. Juni 2025

Artikel dieses Verkäufers ansehen
Hardcover

Zustand: Neu

EUR 157,16

EUR 43,06 Versand 
Versand innerhalb von USA

Anzahl: Mehr als 20 verfügbar

In den Warenkorb
Kostenlose Rückgaben innerhalb von 30 Tagen

Artikelbeschreibung vom Verkäufer

The understanding, at the molecular level, of the interactions between innate and adaptive arms of the immune system is currently a hot topic, particularly to those interested in immunology - especially susceptibility to infectious diseases. This book provides a survey of topics, in the area of innate and adaptive immunity, which have been researched within the MRC Immunochemistry Unit, at Oxford University, over a period of forty years. The topics include: "antibody structure - for which the first Director of the Immunochemistry Unit, Professor RR Porter, was awarded a Nobel prize in 1972 "the characterization of membrane proteins on lymphoid cells - leading to the concept of these molecules belonging to an immunoglobulin super family "the proteins of the human serum complement system - one of the body's major defences against microbial infection "the human cell -surface integrins and the hyaluronan- binding proteins, which are involved in regulation of inflammation at cell surfaces and within the extracellular matrix "the family of collectin molecules - containing distinct globular carbohydrate -binding domains linked to collagen-like regions - which play important roles in innate immunity in the lungs and bloodstream by immediate recognition and clearance of microbial pathogens Each chapter in the book gives a brief historical background to a topic and then provides a survey of recent advances in the field and are written by internationally recognised renowned experts. The theme running through the chapters is that of protein structure-function relationships - including, amongst others, descriptions of quaternary structures of large oligomeric proteins, of Factor H and C1q binding to specific ligands, and of the chemistry of the mechanism of catalysis of covalent binding of activated C3 and C4 proteins to nucleophilic groups on microbial surfaces. In several chapters excellent descriptions are given with respect to how the immune system can be recruited to combat microbial infection - via proteins of both the innate and adaptive immune systems. The book also includes notable chapters which are excellent examples of the importance of how the isolation, characterisation, protein engineering and crystallisation has resulted in a full understanding of complex protein-protein interactions involved in the recognition and triggering events of important sections of the immune system: -Structure and Function of the C1 Complex - GÚrard J. Arlaud -Chemical Engineering of Therapeutic Antibodies - George T Stevenson -Leukocyte surface proteins - purification and characterisation - A. Neil Barclay -Cell Surface Integrins - Suet-Mien Tan and S.K. Alex Law This book is aimed primarily at established senior research scientists, postdoctoral research scientists and PhD students who have an interest in proteins of the immune system. However, the wide range of immunity system topics, while staying broadly within innate/adaptive immunity will also appeal to a wide.

Bestandsnummer des Verkäufers LU-9780854046980

Titel
Molecular Aspects of Innate and Adaptive Immunity
Autor
Kenneth B M Reid
Verlag
Royal Society of Chemistry, GB
Veröffentlichungsjahr
2008
Zustand
New
Einband
Hardback
Sprache
Englisch
ISBN-10
0854046984
ISBN-13
9780854046980
Artikelgewicht
631 Gramm

Rarewaves USA United

HEBRON, KY, USA

Verkäufer/-in mit 5 Sternen

AbeBooks-Verkäufer/-in seit 20. Juni 2025

Versandkosten innerhalb von USA

Artikel30 bis 30 Werktage14 bis 14 Werktage
Erster ArtikelEUR 43,06EUR 57,70
Die Versandzeiten werden von den Verkäuferinnen und Verkäufern festgelegt. Sie variieren je nach Versanddienstleister und Standort. Sendungen, die den Zoll passieren, können Verzögerungen unterliegen. Eventuell anfallende Abgaben oder Gebühren sind von der Käuferin bzw. dem Käufer zu tragen. Die Verkäuferin bzw. der Verkäufer kann Sie bezüglich zusätzlicher Versandkosten kontaktieren, um einen möglichen Anstieg der Versandkosten für Ihre Artikel auszugleichen.

Zahlungsarten

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay

Unternehmensdaten der Verkäuferin bzw. des Verkäufers

Rarewaves USA

10100 West Sample Road, Ste 101
Coral Springs, FL USA 33065