An Overview of Genetic Factors and Environmental Triggers in the Pathogenesis of Tourette's Syndrome

Zhimin Miao Shi-guo Liu Qian Dong Ping Yang Cong-yi Wang

ISBN 10: 1616687487 / ISBN 13: 9781616687489

Verlag: Nova Science Publishers, Incorporated, 2010

Beschreibung

pp. xii + 59 Index. Bestandsnummer des Verkäufers 261297531

Bibliografische Details

Titel: An Overview of Genetic Factors and ...

Verlag: Nova Science Publishers, Incorporated

Erscheinungsdatum: 2010

Einband: Softcover

Zustand: Used

Über diesen Titel

Inhaltsangabe:

Tourette's syndrome (TS) is an inheritable, childhood-onset neuropsychiatric disorder characterised by the presence of motor and phonic tics. Despite decades of extensive studies, the exact disease aetiology remains poorly understood. It is believed that susceptibility to TS is determined by the interactions of multiple genetic loci with unknown environmental factors. As a result, a great deal of research has been focused on identifying TS susceptibility genes. Thus far, at least 12 susceptibility loci have been suggested by genome-wide screenings, but none of them has been replicated probably due to genetic heterogeneity. Candidate gene approach has also suggested evidence for several genes relevant to neuronal signalling such as dopamine receptor and serotonin receptor. This book discusses the current state of genetic studies in TS susceptibility.

Über die Autorin bzw. den Autor:

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.