PCR Mutation Detection Protocols

Theophilus Bimal D. M.

ISBN 10: 0896036170 / ISBN 13: 9780896036178

Verlag: Humana Press, 2002

Beschreibung

pp. x + 212. Bestandsnummer des Verkäufers 18290062

Bibliografische Details

Titel: PCR Mutation Detection Protocols

Verlag: Humana Press

Erscheinungsdatum: 2002

Einband: Softcover

Zustand: Used

Über diesen Titel

Inhaltsangabe:

Bimal D. Theophilus and Ralph Rapley provide biological and clinical investigators with a comprehensive collection of new, recent, and updated PCR-based screening methods suitable for detecting the presence of both known and novel mutations. The methods cover point mutations (e.g., ASO-PCR, SSCP, DGGE, chemical cleavage), deletions (multiplex PCR, FISH, blotting), non-sense mutations (PTT), and more. The new and exciting techniques of DNA array analysis, along with such recently developed experimental methods as conformation-sensitive gel electrophoresis, are also included. Each chapter explains the basic theory behind the technique and provides valuable notes essential for its successful execution.

Críticas:

"The book provides access to the highly productive and readily reproducible PCR-based mutation detection methods, that are behind many of today's major scientific and medical advances." - Clinical Laboratory International