Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I: 264/1 (Current Topics in Microbiology and Immunology, 264/1) [Hardcover] Hacker, J. and Kaper, J.B.

ISBN 10: 3540426817 / ISBN 13: 9783540426813

Verlag: Springer, 2002

Beschreibung

Used, some outer edges and corners have minor scuffs, cover has light scratches, book content is in very good condition.

Bestandsnummer des Verkäufers 090440-6

Bibliografische Details

• Titel: Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I: 264/1 (Current Topics in Microbiology and Immunology, 264/1) [Hardcover] Hacker, J. and Kaper, J.B.
• Verlag: Springer
• Erscheinungsjahr: 2002
• Sprache: Englisch
• ISBN-10: 3540426817
• ISBN-13: 9783540426813
• Einband: Hardcover
• Zustand: Very Good

Über diesen Titel

Inhaltsangabe

It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

Críticas

From the reviews:

"In addition to classic mutational events, a highly successful strategy of generating genetic diversity in bacteria is the acquisition of genomic islands. ... This compendium ... features an international assembly of authors including W. Arber (Basel) giving a lucid introduction into the evolution of prokaryotic genomes. The two-volume work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants." (Susanne Rohrer, BioWorld, Issue 6, 2002)