Personalized Drug Screening for Functional Tumor Profiling

Victoria El-Khoury , Tatiana Michel , Hichul Kim , Yong-Jun Kwon

ISBN 10: 1009016938 / ISBN 13: 9781009016933

Verlag: Cambridge University Press, 2022

Beschreibung

75 pages. 8.90x5.98x0.28 inches. In Stock.

Bestandsnummer des Verkäufers x-1009016938

Bibliografische Details

• Titel: Personalized Drug Screening for Functional Tumor Profiling
• Verlag: Cambridge University Press
• Erscheinungsjahr: 2022
• Sprache: Englisch
• ISBN-10: 1009016938
• ISBN-13: 9781009016933
• Einband: Paperback
• Zustand: Brand New

Über diesen Titel

Inhaltsangabe

Despite considerable advances in our understanding of the biology that underlies tumor development and progression of cancer and the rapidly evolving field of personalized medicine, cancer is still one of the deadliest diseases. Many cancer patients have benefited from the survival improvements observed with targeted therapies but only a small subset of patients receiving targeted drugs experience an objective response. Because cancer is a complex and heterogeneous disease, the search for effective cancer treatments will need to address not only patient-specific molecular defects but also aspects of the tumor microenvironment. The functional tumor profiling directly measures the cellular phenotype, in particular tumor growth, in response to drugs using patient-derived tumor models and might be the next step toward precision oncology. In this Element, the authors discuss the personalized drug screening as a novel patient stratification strategy for the determination of individualized treatment choices in oncology.

Über die Autorin bzw. den Autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.