Pharmacokinetic and Pharmacodynamic Data Analysis : Concepts and Applications

Gabrielsson, Johan L., Weiner, Daniel L.

Verlag: Swedish Pharmaceutical Press, 1998
ISBN 10: 9186274694 / ISBN 13: 9789186274696
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Inhaltsangabe: This text begins with a basic introduction to pharmacokinetics and pharmacodynamic modelling principles for scientists with minimal formal training in the area. The theory is explained through the use of diagrams and graphics amd complex mathematical models are kept to a minimum. Underlying principles, such as clearance, potency, tolerance, weighting and search algorithms and issues of programme validation are also discussed. This revised second edition text offers expanded sections on pharmacokinetic and pharmacodynamic theory and modelling concepts. There are chapters on NCA, non-linear kinetics (capacity, time, flow and binding), turnover concepts, pulsative functions, push-and-pull and precursor models. Determination of initial parameter estimates for complex models, binding and displacement models and toxicokinetic models are also included.

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Titel: Pharmacokinetic and Pharmacodynamic Data ...
Verlag: Swedish Pharmaceutical Press
Erscheinungsdatum: 1998
Zustand: very good

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Johan L. Gabrielsson, Daniel Weiner
Verlag: Swedish Pharmaceutical Press, United Kingdom (2016)
ISBN 10: 9198299107 ISBN 13: 9789198299106
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Buchbeschreibung Swedish Pharmaceutical Press, United Kingdom, 2016. Hardback. Buchzustand: New. 5th Revised edition. 241 x 171 mm. Language: English . Brand New Book. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaption and rebound, dose-response-time data analysis, inter-species scaling and a lot more. A substantial effort has been invested into the new pharmacokineticsand pharmacodynamics, including many new and updated Case Studies. The text develops a logical, real-world approach to data and reasoning, showing the reader how to: Think both analytically and visually about data Use graphics to make a point Impove your pattern recognition ability Make sound decisions Strategize your data analyses Appreciate more fully the exciting field of Quantitative Pharmacology. Buchnummer des Verkäufers AA69789198299106

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2.

Johan L. Gabrielsson, Daniel Weiner
Verlag: Swedish Pharmaceutical Press, United Kingdom (2016)
ISBN 10: 9198299107 ISBN 13: 9789198299106
Neu Hardcover Anzahl: 10
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(London, Vereinigtes Königreich)
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Buchbeschreibung Swedish Pharmaceutical Press, United Kingdom, 2016. Hardback. Buchzustand: New. 5th Revised edition. 241 x 171 mm. Language: English . Brand New Book. Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications teaches everyday biological data analysis to the undergraduate and graduate levels. Through numerous examples and over 100 tutorials, scientists learn how to use PK/PD seamlessly in a variety of practical areas, from simple plasma kinetics, multi-compartment models, nonlinear kinetics, plasma protein binding, pharmacodynamic models, turnover concepts, receptor binding, functional adaption and rebound, dose-response-time data analysis, inter-species scaling and a lot more. A substantial effort has been invested into the new pharmacokineticsand pharmacodynamics, including many new and updated Case Studies. The text develops a logical, real-world approach to data and reasoning, showing the reader how to: Think both analytically and visually about data Use graphics to make a point Impove your pattern recognition ability Make sound decisions Strategize your data analyses Appreciate more fully the exciting field of Quantitative Pharmacology. Buchnummer des Verkäufers AA69789198299106

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