Pharmacologic Analysis of Drug-Receptor Interaction. Dieser Artikel ist nicht verfügbar.Pharmacologic Analysis of Drug-Receptor Interaction

This second edition aims to be a valuable resource for all researchers involved in the drug design and development process. Not only has the text been updated and revised, but reflecting the significant technical breakthroughs of recent years, it now more generally encompasses all receptor systems, whether derived from molecular biology or whole animal studies. These systems are examined within the framework of current drug receptor theories, particularly the receptor occupation theory, the operational model of drug action and the ternary complex model. The rigorous evaluation of receptor systems; the measurement of drug response; the statistical treatment of data; the application of data to receptor models; all are considered from the unifying aspect of using the data to develop new drugs for optimal therapeutic advantage. This edition also reviews current procedures for determining whether drug selectivity is a function of the receptors, or the result of the collective properties of the drug, receptor and tissue host.