Process Development : Fine Chemicals from Grams to Kilograms

Stan Lee

ISBN 10: 0198558244 / ISBN 13: 9780198558248

Verlag: OUP Oxford, 1995

Beschreibung

nach der Bestellung gedruckt Neuware - Printed after ordering - Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. This concise and readable text uses real examples and case histories from ICI/Zeneca Pharmaceuticals to show the problems which may be encountered in scaling up chemical synthesis, and the ways these problems may be overcome. It shows how it is possible to synthesize multi-kilogram quantities of a new organic compound which has been made in the laboratory only in the milligram scale. A wide range of aliphatic, aromatic, and heterocyclic compounds is covered. This book will be invaluable both to the research chemist involved in the development phase of novel compounds, and the advanced undergraduate interested in the fine chemicals industry.

Bestandsnummer des Verkäufers 9780198558248

Bibliografische Details

• Titel: Process Development : Fine Chemicals from Grams to Kilograms
• Verlag: OUP Oxford
• Erscheinungsjahr: 1995
• Sprache: Englisch
• ISBN-10: 0198558244
• ISBN-13: 9780198558248
• Einband: Taschenbuch
• Zustand: Neu

Über diesen Titel

Inhaltsangabe

Process development bridges the gap between the laboratory synthesis of an organic compound and its industrial manufacture on a large scale. In this concise text the authors use real examples to show the problems which may be encountered in scaling up chemical syntheses and the ways in which these problems may be overcome. The major part of the book is devoted to genuine case histories from ICI/Zeneca Pharmaceuticals. Through a range of carefully chosen examples, the book explains how it is possible to synthesise multi-kilogram quantities of a new organic compound which have been made in the laboratory only on the milligram scale. A wide range of aliphatic, aromatic, and heterocyclic compounds is covered. The book will be of particular value to research chemists who are involved in the development phase of novel compounds and to advanced undergraduate and postgraduate students interested in the fine chemicals industry.

Über die Autorin bzw. den Autor

Stan Lee and Graham Robinson are both at Zeneca Pharmaceuticals, Macclesfield, Cheshire.