Proteases : From Basic Structure to Function to Drug Design as Targeted Therapy

ISBN 10: 3036525750 / ISBN 13: 9783036525754

Verlag: MDPI AG, 2021

Beschreibung

nach der Bestellung gedruckt Neuware - Printed after ordering - In the two last decades, proteases have constituted one of the primary and important targets in drug discovery. The U.S. FDA has approved more than 12 protease therapies in the last 10 years, and a number of next-generation or completely new proteases are under clinical development. Protease inhibition strategies are one of the fastest expanding areas in the field of of drugs that show considerable promise. This Special Issue will focus on the recent advances in the discovery and development of protease inhibitors, covering the synthesis of protease inhibitors, the design of new chemical entities acting as inhibitors of special/particular types of proteases, and their mode of actions (Frolova et al. 2020; Slapak et al. 2020; Künnapuu et al. 2021). In addition, the new applications of these interesting compounds/biomolecules and their limitations have been discussed and described (Wang et al. 2020; Barto ová-Sojková et al. 2021).

Bestandsnummer des Verkäufers 9783036525754

Bibliografische Details

• Titel: Proteases : From Basic Structure to Function to Drug Design as Targeted Therapy
• Verlag: MDPI AG
• Erscheinungsjahr: 2021
• Sprache: Englisch
• ISBN-10: 3036525750
• ISBN-13: 9783036525754
• Einband: Buch
• Zustand: Neu
• Abmessungen: 250B x 175 H x 12 T Millimeter Breite: 250 mm, Höhe: 175 mm, Tiefe: 12 mm
• Gewicht: 470 Gramm

Über diesen Titel

Inhaltsangabe

In the two last decades, proteases have constituted one of the primary and important targets in drug discovery. The U.S. FDA has approved more than 12 protease therapies in the last 10 years, and a number of next-generation or completely new proteases are under clinical development. Protease inhibition strategies are one of the fastest expanding areas in the field of of drugs that show considerable promise. This Special Issue will focus on the recent advances in the discovery and development of protease inhibitors, covering the synthesis of protease inhibitors, the design of new chemical entities acting as inhibitors of special/particular types of proteases, and their mode of actions (Frolova et al. 2020; Slapak et al. 2020; Künnapuu et al. 2021). In addition, the new applications of these interesting compounds/biomolecules and their limitations have been discussed and described (Wang et al. 2020; Bartosová-Sojková et al. 2021).