Ranaviruses | Emerging Pathogens of Ectothermic Vertebrates. Dieser Artikel ist nicht verfügbar.Ranaviruses | Emerging Pathogens of Ectothermic Vertebrates

This is a open access book. Ranaviruses, double-stranded DNA viruses (family Iridoviridae) that cause systemic, life-threatening disease in a variety of amphibians, reptiles and fish, have contributed to mass die-offs of both wild and captive populations around the globe.  These viruses are emerging and increasingly responsible for population declines of ectothermic vertebrates.  Because amphibians, reptiles, and freshwater turtles are suitable hosts and among the most imperiled vertebrate taxa in the world, ranaviruses can have significant impacts on biodiversity and ecosystem function.  Additionally, many fish that are raised in aquaculture facilities and traded internationally are suitable hosts; thus, the potential economic impact of ranaviruses is significant.  Ranaviruses also serve as a model for understanding viral replication and gene function among large double-stranded DNA viruses, e.g., poxviruses, asfarvirus, and ascoviruses.  Lastly, study of the host immune response to ranaviral disease and the identification of viral immune evasion genes that negatively regulate host immune functions provide insight into which specific immune elements are most important in protecting host species against severe disease.

The effort to produce a 2nd edition of our earlier work grew out of a recent meeting (1st Global Amphibian and Reptile Disease Conference) held in August 2022.  Given the continued research in ranaviruses and ranaviral disease since the first edition, this new book updates the latest information on ranaviruses and provides guidance on how to monitor and manage ranaviruses in cold-blooded vertebrate populations. 

M.J. Gray is a professor of disease ecology at the University of Tennessee and has studied amphibian pathogens for >20 years. He is the founding director of the Global Ranavirus Consortium and Healthy Trade Institute. He has served as an associate editor of the Journal of Wildlife Management (Wiley-Blackwell) and co-edited the first edition of Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates.  

V.G. Chinchar, Professor Emeritus, has been active in ranavirus studies for over 40 years.  He has served as an associate editor of Diseases of Aquatic Organisms (Inter-Research) and as a reviewer for  Archives of Virology (Springer), Veterinary Pathology,  Developmental and Comparative Immunology (Elsevier), and Viruses (MDPI AG).  He currently serves on the editorial board of the Journal of Virology (Am. Soc. Microbiology).  He  was a guest editor for special issues of Viruses (MDPI AG) and Virology focused on iridoviruses and co-edited the first edition of Ranaviruses: Lethal Pathogens of Ectothermic Vertebrates.