Scientific and Clinical Applications of Magnetic Carriers

Hafeli, Urs; Schutt, Wolfgang; Teller, Joachim; Zborowski, Maciej

ISBN 10: 1441932836 / ISBN 13: 9781441932839

Verlag: Springer, 2010

Bestandsnummer des Verkäufers 11877929-n

Inhaltsangabe:

The discovery of uniform latex particles by polymer chemists of the Dow Chemical Company nearly 50 years ago opened up new exciting fields for scientists and physicians and established many new biomedical applications. Many in vitro diagnostic tests such as the latex agglutination tests, analytical cell and phagocytosis tests have since become rou tine. They were all developed on the basis of small particles bound to biological active molecules and fluorescent and radioactive markers. Further developments are ongoing, with the focus now shifted to applications of polymer particles in the controlled and di rected transport of drugs in living systems. Four important factors make microspheres interesting for in vivo applications: First, biocompatible polymer particles can be used to transport known amounts of drug and re lease them in a controlled fashion. Second, particles can be made of materials which bio degrade in living organisms without doing any harm. Third, particles with modified surfaces are able to avoid rapid capture by the reticuloendothelial system and therefore en hance their blood circulation time. Fourth, combining particles with specific molecules may allow organ-directed targeting.

Bibliografische Details

Titel: Scientific and Clinical Applications of ...
Verlag: Springer
Erscheinungsdatum: 2010
Einband: Softcover
Zustand: New