Statistics and Data Analysis for Microarrays Using R and Bioconductor (Chapman & Hall/CRC Computational Biology Series)

Drăghici, Sorin

ISBN 10: 1439809755 / ISBN 13: 9781439809754

Verlag: Chapman and Hall/CRC, 2011

Beschreibung

Bestandsnummer des Verkäufers Shelfdream1439809755

Bibliografische Details

• Titel: Statistics and Data Analysis for Microarrays Using R and Bioconductor (Chapman & Hall/CRC Computational Biology Series)
• Verlag: Chapman and Hall/CRC
• Veröffentlichungsdatum: 2011
• Sprache: Englisch
• ISBN-10: 1439809755
• ISBN-13: 9781439809754
• Bindung: Hardcover
• Ausgabe: 2. Auflage
• Zustand: New

Über diesen Titel

Inhaltsangabe

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that teaches students the basics of R and microarray technology as well as how to choose and apply the proper data analysis tool to specific problems.

New to the Second EditionCompletely updated and double the size of its predecessor, this timely second edition replaces the commercial software with the open source R and Bioconductor environments. Fourteen new chapters cover such topics as the basic mechanisms of the cell, reliability and reproducibility issues in DNA microarrays, basic statistics and linear models in R, experiment design, multiple comparisons, quality control, data pre-processing and normalization, Gene Ontology analysis, pathway analysis, and machine learning techniques. Methods are illustrated with toy examples and real data and the R code for all routines is available on an accompanying downloadable resource.

With all the necessary prerequisites included, this best-selling book guides students from very basic notions to advanced analysis techniques in R and Bioconductor. The first half of the text presents an overview of microarrays and the statistical elements that form the building blocks of any data analysis. The second half introduces the techniques most commonly used in the analysis of microarray data.

Über die Autorin bzw. den Autor

Sorin Drăghici the Robert J. Sokol MD Endowed Chair in Systems Biology in the Department of Obstetrics and Gynecology, professor in the Department of Clinical and Translational Science and Department of Computer Science, and head of the Intelligent Systems and Bioinformatics Laboratory at Wayne State University. He is also the chief of the Bioinformatics and Data Analysis Section in the Perinatology Research Branch of the National Institute for Child Health and Development. A senior member of IEEE, Dr. Drăghici is an editor of IEEE/ACM Transactions on Computational Biology and Bioinformatics, Journal of Biomedicine and Biotechnology, and International Journal of Functional Informatics and Personalized Medicine. He earned a Ph.D. in computer science from the University of St. Andrews.