Stochastic Models With Applications to Genetics, Cancers, AIDS, and Other Biomedical Systems

Tan, Wai-yuan

ISBN 10: 9814390941 / ISBN 13: 9789814390941

Verlag: World Scientific Pub Co Inc, 2012

Beschreibung

2nd edition. 600 pages. 9.13x6.57x1.11 inches. In Stock.

Bestandsnummer des Verkäufers x-9814390941

Bibliografische Details

• Titel: Stochastic Models With Applications to Genetics, Cancers, AIDS, and Other Biomedical Systems
• Verlag: World Scientific Pub Co Inc
• Erscheinungsjahr: 2012
• Sprache: Englisch
• ISBN-10: 9814390941
• ISBN-13: 9789814390941
• Einband: Hardcover
• Auflage: 2. Auflage
• Zustand: Brand New

Über diesen Titel

Inhaltsangabe

 

 

This book presents a systematic treatment of Markov chains, diffusion processes and state space models, as well as alternative approaches to Markov chains through stochastic difference equations and stochastic differential equations. It illustrates how these processes and approaches are applied to many problems in genetics, carcinogenesis, AIDS epidemiology and other biomedical systems.

One feature of the book is that it describes the basic MCMC (Markov chain and Monte Carlo) procedures and illustrates how to use the Gibbs sampling method and the multilevel Gibbs sampling method to solve many problems in genetics, carcinogenesis, AIDS and other biomedical systems.

As another feature, the book develops many state space models for many genetic problems, carcinogenesis, AIDS epidemiology and HIV pathogenesis. It shows in detail how to use the multilevel Gibbs sampling method to estimate (or predict) simultaneously the state variables and the unknown parameters in cancer chemotherapy, carcinogenesis, AIDS epidemiology and HIV pathogenesis. As a matter of fact, this book is the first to develop several state space models for many genetic problems, carcinogenesis and other biomedical problems.

To emphasize special applications to medical problems, in this new edition the book has added a new chapter to illustrate how to develop biologically-supported stochastic models and state space models of carcinogenesis in human beings. Specific examples include hidden Markov models and state space models for human colon cancer, human liver cancer and some human pediatric cancers such as retinoblastoma and hepatoblastoma. The book also gives examples to illustrate how to develop procedures to assess cancer risk of environmental agents through initiation-promotion protocols.

Über die Autorin bzw. den Autor

Charlotte y Peter Fiell son dos autoridades en historia, teoría y crítica del diseño y han escrito más de sesenta libros sobre la materia, muchos de los cuales se han convertido en éxitos de ventas. También han impartido conferencias y cursos como profesores invitados, han comisariado exposiciones y asesorado a fabricantes, museos, salas de subastas y grandes coleccionistas privados de todo el mundo. Los Fiell han escrito numerosos libros para TASCHEN, entre los que se incluyen 1000 Chairs, Diseño del siglo XX, El diseño industrial de la A a la Z, Scandinavian Design y Diseño del siglo XXI.