This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings. In fair condition, suitable as a study copy. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1250grams, ISBN:9781420063226.

Bestandsnummer des Verk�ufers 7062182

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Bibliografische Details

Titel

Textbook of Drug Design and Discovery (Fourth Edition)

Verlag

CRC

Erscheinungsjahr

2010

Sprache

Englisch

ISBN-10

1420063227

ISBN-13

9781420063226

Einband

Hardcover

Auflage

4. Auflage

Zustand

Fair

Gewicht

1250 Gramm

Verk�uferkataloge

Medicine

�ber diesen Titel

Inhaltsangabe

The molecular biological revolution and the mapping of the human genome continue to provide new challenges and opportunities for drug research and design. Future medicinal chemists and drug designers must have a firm background in a number of related scientific disciplines in order to understand the conversion of new insight into lead structures and subsequently into drug candidates. Classroom tested and student approved, Textbook of Drug Design and Discovery, Fourth Edition describes the manner in which medicinal chemists utilize the various fields upon which they draw and the specific strategies they employ to advance promising molecules into clinical use for the treatment of disease.

This text integrates a number of related scientific disciplines, including advanced synthetic chemistry, computational chemistry, biochemistry, structural biology, and molecular pharmacology, to provide current and comprehensive information on all aspects of drug design and discovery.

Extensively revised, new topics in the fourth edition include:

Biostructure-based and ligand-based drug design
Chemical biology
Natural products
Imaging
Neurotransmitter transporters
Opioid and cannabinoid receptors
Hypnotics
Neglected diseases
Immunomodulating agents
Antibiotics

The first part of the book covers general aspects, methods, and principles for drug design and discovery, and the second part covers specific targets and diseases. The text contains more than 300 color figures and 24 tables for rapid assimilation. Each chapter includes references for further study. Most chapters also provide the background and history needed to provide a context for students, as well as conclusions that summarize the points most relevant to emerging areas of research in drug design.

�ber die Autorin bzw. den Autor

Povl Krogsgaard-Larsen is a professor of medicinal chemistry in the Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, at the University of Copenhagen. Kristian Str�mgaard is a professor of chemical biology in the Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, at the University of Copenhagen. Ulf Madsen is currently an associate dean in the Faculty of Pharmaceutical Sciences at the University of Copenhagen.

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