Inhaltsangabe
Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.
Críticas
"Describing all facets of modern drug design and development, this major textbook is an invaluable source of information for students of chemistry, phamacology, pharmacy, medicinal chemistry, medicine and biochemistry at all levelsAlmost every page is illustrated with figures, tables and structural formulae." Unlisted Drugs "A well-structured and informative book" S. Damment, Glaxo, Newsletter of British Society for Toxicology "Excellent bookThe editors set a high standard." Professor Graham Johnston, TiPS "a good and substantial bookgood introductions to many aspects of a complex subject" Chris Ramsden, Chemistry and Industry
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