Chengxing (27 Ergebnisse)
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Master Protocol Clinical Trials for Evidence Generation : Strategies, Designs, Operations, and Case Studies
Lu, Ruixiao (EDT); Ye, Jingjing (EDT); Lu, Chengxing (EDT); Wang, William (EDT)
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Master Protocol Clinical Trials for Evidence Generation : Strategies, Designs, Operations, and Case Studies
Lu, Ruixiao (EDT); Ye, Jingjing (EDT); Lu, Chengxing (EDT); Wang, William (EDT)
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Master Protocol Clinical Trials for Evidence Generation : Strategies, Designs, Operations, and Case Studies
Lu, Ruixiao (EDT); Ye, Jingjing (EDT); Lu, Chengxing (EDT); Wang, William (EDT)
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Master Protocol Clinical Trials for Evidence Generation : Strategies, Designs, Operations, and Case Studies
Lu, Ruixiao (EDT); Ye, Jingjing (EDT); Lu, Chengxing (EDT); Wang, William (EDT)
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Zustand: New. Ruixiao LuDr. Ruixiao Lu is a recognized leader in the biotech and biopharma industry, currently serving as Vice President, Head of Biostatistics & Statistical Programming at Alumis Inc. She has held senior leadership roles at various c.
Master Protocol Clinical Trials for Evidence Generation: Strategies, Designs, Operations, and Case Studies
Lu, Ruixiao (Editor)/ Ye, Jingjing (Editor)/ Lu, Chengxing (Editor)/ Wang, William (Editor)
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Buch. Zustand: Neu. Neuware - Drug development is at a crossroads. As personalized medicine and targeted therapies expand, traditional clinical trial models have become too slow, costly, and inefficient. To meet the urgent need for faster, reliable evidence generation and decision making, researchers and regulators alike have tu…rned to innovative trial designs. Among these, master protocols stand out as a transformative approach, allowing multiple therapies, disease subtypes, or objectives to be studied under a single, integrated framework. Proven successful in oncology, COVID-19, and beyond, they improve efficiency, reduce participant exposure to ineffective treatments, and accelerate meaningful outcomes with patient centric approach, prompting regulatory guidance and global adoption.This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples such as I-SPY, ROAR, and RECOVERY. A practical guide for researchers, statisticians, regulators, and industry professionals, it demonstrates how master protocols can reshape drug development and bring innovative therapies to patients faster.¿ Provides comprehensive, theoretical and practical aspects for master protocol trials¿ Includes most recent development in the master protocol clinical trials¿ Covers broad topics such as trial designs, governance oversight, software implementation, database and data pipeline, multi-regional trials, risk and benefit with operational solutions, economic considerations, regulatory perspectives, patient engagement and diversity¿ Deep dives into numerous real world case studies, their underlying thinking, challenges and success.¿ Includes global perspective in multi-regional clinical development.
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Hardcover. Zustand: new. Hardcover. Special Issue 'Additive Manufacturing of Fibre-Reinforced Polymer Composites' has 13 pioneering studies advancing AM-FRPCs. Covering aerospace, automotive, energy, sustainability, it presents integration of novel materials, process/structural innovations, smart functionalities. It shows AM ena…bles complex geometries, multifunctional parts with tailored mechanical, thermal, sensing properties. Articles address interlaminar toughness, porosity, fibre misalignment via nano-fillers, hybrid reinforcements, optimised paths. The highlights include laser-induced graphene for real-time damage sensing; eco-friendly biocomposites (chem-treated natural fibres); and spatial 3D printing for low-density, high-strength trusses. Mechanical testing uses experimental/numerical methods: acoustic emission, digital image correlation, finite element simulation, and Taguchi optimisation. Integrating AI and neural networks in print tuning and performance prediction marks a shift to intelligent manufacturing. From boosting buckling in anisotropic grids to refining laser-sintering via thermal simulation, this Special Issue offers insights into current research and future opportunities in process control, defect mitigation, and in situ monitoring. It is a timely collection of scientific breakthroughs and engineering practices driving next-gen FRPCs via AM, aiding researchers, engineers, and designers using AM's unique high-performance composite advantages. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
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Buch. Zustand: Neu. Additive Manufacturing of Fibre Reinforced Polymer Composites | Buch | Englisch | 2025 | MDPI AG | EAN 9783725857319 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.
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Hardcover. Zustand: new. Hardcover. Drug development is at a crossroads. As personalized medicine and targeted therapies expand, traditional clinical trial models have become too slow, costly, and inefficient. To meet the urgent need for faster, reliable evidence generation and decision making, researchers and regulators alike h…ave turned to innovative trial designs. Among these, master protocols stand out as a transformative approach, allowing multiple therapies, disease subtypes, or objectives to be studied under a single, integrated framework. Proven successful in oncology, COVID-19, and beyond, they improve efficiency, reduce participant exposure to ineffective treatments, and accelerate meaningful outcomes with patient centric approach, prompting regulatory guidance and global adoption.This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples such as I-SPY, ROAR, and RECOVERY. A practical guide for researchers, statisticians, regulators, and industry professionals, it demonstrates how master protocols can reshape drug development and bring innovative therapies to patients faster. Provides comprehensive, theoretical and practical aspects for master protocol trials Includes most recent development in the master protocol clinical trials Covers broad topics such as trial designs, governance oversight, software implementation, database and data pipeline, multi-regional trials, risk and benefit with operational solutions, economic considerations, regulatory perspectives, patient engagement and diversity Deep dives into numerous real world case studies, their underlying thinking, challenges and success. Includes global perspective in multi-regional clinical development This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Hardcover. Zustand: new. Hardcover. Drug development is at a crossroads. As personalized medicine and targeted therapies expand, traditional clinical trial models have become too slow, costly, and inefficient. To meet the urgent need for faster, reliable evidence generation and decision making, researchers and regulators alike h…ave turned to innovative trial designs. Among these, master protocols stand out as a transformative approach, allowing multiple therapies, disease subtypes, or objectives to be studied under a single, integrated framework. Proven successful in oncology, COVID-19, and beyond, they improve efficiency, reduce participant exposure to ineffective treatments, and accelerate meaningful outcomes with patient centric approach, prompting regulatory guidance and global adoption.This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples such as I-SPY, ROAR, and RECOVERY. A practical guide for researchers, statisticians, regulators, and industry professionals, it demonstrates how master protocols can reshape drug development and bring innovative therapies to patients faster. Provides comprehensive, theoretical and practical aspects for master protocol trials Includes most recent development in the master protocol clinical trials Covers broad topics such as trial designs, governance oversight, software implementation, database and data pipeline, multi-regional trials, risk and benefit with operational solutions, economic considerations, regulatory perspectives, patient engagement and diversity Deep dives into numerous real world case studies, their underlying thinking, challenges and success. Includes global perspective in multi-regional clinical development This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples. This item is printed on demand. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.
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Hardcover. Zustand: new. Hardcover. Drug development is at a crossroads. As personalized medicine and targeted therapies expand, traditional clinical trial models have become too slow, costly, and inefficient. To meet the urgent need for faster, reliable evidence generation and decision making, researchers and regulators alike h…ave turned to innovative trial designs. Among these, master protocols stand out as a transformative approach, allowing multiple therapies, disease subtypes, or objectives to be studied under a single, integrated framework. Proven successful in oncology, COVID-19, and beyond, they improve efficiency, reduce participant exposure to ineffective treatments, and accelerate meaningful outcomes with patient centric approach, prompting regulatory guidance and global adoption.This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples such as I-SPY, ROAR, and RECOVERY. A practical guide for researchers, statisticians, regulators, and industry professionals, it demonstrates how master protocols can reshape drug development and bring innovative therapies to patients faster. Provides comprehensive, theoretical and practical aspects for master protocol trials Includes most recent development in the master protocol clinical trials Covers broad topics such as trial designs, governance oversight, software implementation, database and data pipeline, multi-regional trials, risk and benefit with operational solutions, economic considerations, regulatory perspectives, patient engagement and diversity Deep dives into numerous real world case studies, their underlying thinking, challenges and success. Includes global perspective in multi-regional clinical development This book provides a multidisciplinary exploration of master protocol clinical trials, blending clinical, statistical, regulatory, operational, economic insights and patients perspectives. It examines both opportunities and challenges in design and implementation, and provides in-depth summary and discussion on real-world examples. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.
