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  • Rezaei, Nima

    Sprache: Englisch

    Verlag: Springer 2023-01, 2023

    ISBN 10: 3031147332 ISBN 13: 9783031147333

    Anbieter: Chiron Media, Wallingford, Vereinigtes Königreich

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    EUR 50,20

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    PF. Zustand: New.

  • Sprache: Englisch

    Verlag: Academic Press, 2024

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Majestic Books, Hounslow, Vereinigtes Königreich

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  • Ghajarzadeh, Mahsa (Editor)/ Hanaei, Sara (Editor)/ Rezaei, Nima (Editor)

    Sprache: Englisch

    Verlag: Academic Pr, 2024

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich

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    EUR 110,05

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    Paperback. Zustand: Brand New. 250 pages. 9.21x7.50x9.25 inches. In Stock.

  • Sprache: Englisch

    Verlag: Academic Press, 2024

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Books Puddle, New York, NY, USA

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    EUR 125,82

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    Zustand: New. 1st edition NO-PA16APR2015-KAP.

  • GHAJARZADEH

    Sprache: Englisch

    Verlag: CHURCHILL LIVINGSTONE, 2025

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Antártica, Madrid, M, Spanien

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    EUR 113,36

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    Rústica. Zustand: New. Zustand des Schutzumschlags: Nuevo. 01. LIBRO.

  • Ghajarzadeh

    Sprache: Englisch

    Verlag: ACADEMIC PRESS, 2024

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Imosver, PONTECALDELAS, PO, Spanien

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    EUR 107,69

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    Zustand: Nuevo. Systematic review and meta-analysis editado por Academic press.

  • Sprache: Englisch

    Verlag: Academic Press, 2024

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Biblios, Frankfurt am main, HESSE, Deutschland

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    EUR 126,59

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    Zustand: New.

  • Nima Rezaei

    Sprache: Englisch

    Verlag: Springer International Publishing AG, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: PBShop.store UK, Fairford, GLOS, Vereinigtes Königreich

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    EUR 139,44

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    PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

  • Rezaei, Nima (EDT); Hanaei, Sara (EDT)

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: GreatBookPrices, Columbia, MD, USA

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    EUR 143,57

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    Zustand: New.

  • Nima Rezaei

    Sprache: Englisch

    Verlag: Springer International Publishing AG, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: PBShop.store US, Wood Dale, IL, USA

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    EUR 145,94

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    PAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.

  • Rezaei, Nima (EDT); Hanaei, Sara (EDT)

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes Königreich

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    EUR 139,43

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    Zustand: New.

  • Rezaei, Nima (EDT); Hanaei, Sara (EDT)

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: GreatBookPrices, Columbia, MD, USA

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    EUR 162,60

    EUR 2,29 Versand
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    Anzahl: 1 verfügbar

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    Zustand: As New. Unread book in perfect condition.

  • REZAEI, NIMA

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: Speedyhen, Hertfordshire, Vereinigtes Königreich

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    EUR 124,09

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    Zustand: NEW.

  • Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: Ria Christie Collections, Uxbridge, Vereinigtes Königreich

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    EUR 162,80

    EUR 13,73 Versand
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    In den Warenkorb

    Zustand: New. In.

  • Rezaei, Nima (EDT); Hanaei, Sara (EDT)

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: GreatBookPricesUK, Woodford Green, Vereinigtes Königreich

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    EUR 162,69

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    Zustand: As New. Unread book in perfect condition.

  • Nima Rezaei (u. a.)

    Sprache: Englisch

    Verlag: Springer, 2024

    ISBN 10: 3031237072 ISBN 13: 9783031237072

    Anbieter: preigu, Osnabrück, Deutschland

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    EUR 111,10

    EUR 70,00 Versand
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    Anzahl: 5 verfügbar

    In den Warenkorb

    Taschenbuch. Zustand: Neu. Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2 | The Path to Bedside Management | Nima Rezaei (u. a.) | Taschenbuch | xxix | Englisch | 2024 | Springer | EAN 9783031237072 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

  • GHAJARZADEH

    Sprache: Englisch

    Verlag: 0-443, 2025

    ISBN 10: 0443134286 ISBN 13: 9780443134289

    Anbieter: Librerias Prometeo y Proteo, Malaga, MA, Spanien

    Verkäuferbewertung 2 von 5 Sternen 2 Sterne, Erfahren Sie mehr über Verkäufer-Bewertungen

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    EUR 113,36

    EUR 70,00 Versand
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    Anzahl: 1 verfügbar

    In den Warenkorb

    Otros. Zustand: New. Zustand des Schutzumschlags: Nuevo. 01. LIBRO.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer Nature Switzerland Aug 2024, 2024

    ISBN 10: 3031237072 ISBN 13: 9783031237072

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    EUR 128,39

    EUR 60,00 Versand
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    Anzahl: 2 verfügbar

    In den Warenkorb

    Taschenbuch. Zustand: Neu. Neuware -This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5¿9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 772 pp. Englisch.

  • Nima Rezaei

    Sprache: Englisch

    Verlag: Springer International Publishing AG, CH, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: Rarewaves.com USA, London, LONDO, Vereinigtes Königreich

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    EUR 199,24

    Versand gratis
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    Anzahl: 1 verfügbar

    In den Warenkorb

    Paperback. Zustand: New. 2023 ed.

  • Nima Rezaei

    Sprache: Englisch

    Verlag: Springer International Publishing AG, Cham, 2023

    ISBN 10: 3031147316 ISBN 13: 9783031147319

    Anbieter: Grand Eagle Retail, Bensenville, IL, USA

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    EUR 202,02

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    Anzahl: 1 verfügbar

    In den Warenkorb

    Hardcover. Zustand: new. Hardcover. Brain tumors comprise about 59% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment. The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, 2024

    ISBN 10: 3031237072 ISBN 13: 9783031237072

    Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland

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    EUR 128,39

    EUR 67,12 Versand
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    Anzahl: 1 verfügbar

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    Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5-9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.

  • Rezaei, Nima (Editor)/ Hanaei, Sara (Editor)

    Sprache: Englisch

    Verlag: Springer Nature, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: Revaluation Books, Exeter, Vereinigtes Königreich

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    EUR 187,21

    EUR 14,33 Versand
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    Anzahl: 1 verfügbar

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    Paperback. Zustand: Brand New. 251 pages. 10.00x7.01x10.00 inches. In Stock.

  • Sprache: Englisch

    Verlag: Springer, 2023

    ISBN 10: 3031147316 ISBN 13: 9783031147319

    Anbieter: Books Puddle, New York, NY, USA

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    EUR 211,94

    EUR 3,46 Versand
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    Anzahl: 4 verfügbar

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    Zustand: New. 1st ed. 2023 edition NO-PA16APR2015-KAP.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, Springer International Publishing Jan 2024, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    EUR 171,19

    EUR 60,00 Versand
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    Anzahl: 2 verfügbar

    In den Warenkorb

    Taschenbuch. Zustand: Neu. Neuware -Brain tumors comprise about 5¿9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment.The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, Springer International Publishing Jan 2023, 2023

    ISBN 10: 3031147316 ISBN 13: 9783031147319

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    EUR 171,19

    EUR 60,00 Versand
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    Anzahl: 2 verfügbar

    In den Warenkorb

    Buch. Zustand: Neu. Neuware -Brain tumors comprise about 5¿9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment.The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 252 pp. Englisch.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, Springer International Publishing Jul 2023, 2023

    ISBN 10: 3031237048 ISBN 13: 9783031237041

    Anbieter: buchversandmimpf2000, Emtmannsberg, BAYE, Deutschland

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    Buch. Zustand: Neu. Neuware -This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5¿9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 772 pp. Englisch.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, Springer International Publishing, 2024

    ISBN 10: 3031147340 ISBN 13: 9783031147340

    Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland

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    Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Brain tumors comprise about 5-9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment.The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, 2023

    ISBN 10: 3031147316 ISBN 13: 9783031147319

    Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland

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    EUR 171,19

    EUR 63,67 Versand
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    In den Warenkorb

    Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Brain tumors comprise about 5-9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment.The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.

  • Unbekannt

    Sprache: Englisch

    Verlag: Springer, 2023

    ISBN 10: 3031147316 ISBN 13: 9783031147319

    Anbieter: Buchpark, Trebbin, Deutschland

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    EUR 132,13

    EUR 105,00 Versand
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    Zustand: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Brain tumors comprise about 5¿9% of all human neoplasms; and interestingly the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. Besides to the morphologic and histopathologic characteristics, and as each pathologic states first starts with molecular alterations, each tumor may have its own story in the matter of activating tumorigenesis pathways and having specific molecular characteristics. Importantly, the molecular classification of tumors has been highly considered in the past few decades for taking the most appropriate therapeutic approach. On the other hand, the tumors shall have tumor-scape mechanisms preventing the immunologic system to eliminate its invasion. The failure of innate and acquired immune system to defeat tumorigenesis mechanisms would consequently result in tumor development. Interestingly, the neuro-immunologic mechanism plays a role in development of psychiatric manifestations of brain tumors as well.Taking all these to account, the different arms of innate immunity, acquired immunity, and genetics have been approached to defeat development and/or progression of such tumors. Accordingly, the activation immunotherapeutic approaches focus on activating or strengthening the anti-tumor immunologic pathways in order to assist the weakened immune system to defeat the tumor (such as Dendritic cell vaccination, DNA vaccines, peptide vaccines, viral vector-based vaccines, monoclonal antibodies, and CAR T-cell therapy). In addition to immunologic components of brain and spinal cord tumors, numerous genes and genetic pathways have been recognized to take part in tumorigenesis. Taking these non-immune genetic pathways to account, some other therapeutic approaches such as stem cell therapy and gene therapy have been developed in the new era of cancer treatment. Moreover, and besides the biologic and medical aspects of these tumors, different physical/mathematical models have been proposed to either explain or predict tumor behavior. Such models would be advantageous in developing new therapeutic modalities in pre-clinical stages and enter new eras in cancer treatment. The first book of Human Brain and Spinal Cord Tumors, Neuro-immunology and Neuro-genetics, will mainly discuss the neuro-immunology and neurogenetic pathways associated with development of brain and spinal cord tumor. After a short introduction chapter, this book will focus on the role of innate and acquired immunity on development of these tumors and then the immunotherapeutic approaches to defeat these tumorigenesis mechanisms. This book will then focus on genetic aspects of brain and spinal cord tumors and bioinformatics models to describe the behavioral patterns of these tumors, as well as associated therapeutic approaches such as stem cell therapy and gene therapy. This volume of book could be useful for experts in basic sciences, mainly geneticists and immunologists, and also physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists and neuroradiologists.

  • Sara Hanaei

    Sprache: Englisch

    Verlag: Springer International Publishing, 2023

    ISBN 10: 3031237048 ISBN 13: 9783031237041

    Anbieter: AHA-BUCH GmbH, Einbeck, Deutschland

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    EUR 171,19

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    In den Warenkorb

    Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5-9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.