Holtzman michael s (29 Ergebnisse)

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Paperback. Zustand: New. Despite remarkable progress, much remains unknown about the risks and benefits of genetic testing. No effective interventions are yet available to improve the outcome of most inherited diseases; negative test results might not rule out future occurrence of disease, and positive test results do not necessarily mean the disease will inevitably develop. In view of this uncertainty, the Working Group on Ethical, Legal, and Social Implications of Human Genome Research at the National Institutes of Health and Department of Energy created the Task Force on Genetic Testing. Comprising representatives of fifteen major stakeholders in genetic testing and five government agencies involved with testing, the task force was charged with reviewing genetic testing in the United States and making recommendations to ensure the development of safe and effective genetic tests. In Promoting Safe and Effective Genetic Testing in the United States the members of this task force present the conclusions of their study. They begin by describing general principles involved in genetic testing, including informed consent, testing of children, confidentiality, and discrimination.They describe methods and policies to ensure the safety and effectiveness of new genetic tests, including criteria for developing tests and ways of ensuring compliance with those criteria. They then discuss how to ensure the quality of laboratories that perform genetic tests, including the role of laboratory personnel and methods of monitoring laboratory performance. They show how health care professionals outside the field of genetics can better understand the uses of genetic testing, and offer suggestions for changes in these professionals' education and training. Finally, they offer a look at testing for rare inherited genetic disorders. Members of the Task Force: Neil A. Holtzman, M.D., M.P.H. * Michael S. Watson, Ph.D., F.A.C.M.G. * Patricia A. Barr * David R. Cox, M.D., M.P.H. * Jessica G. Davis, M.D. * Stephen I. Goodman, M.D., M.Sc. * Wayne W. Grody, M.D., Ph.D. * Arthur L. Levin, M.D. * J. Alexander Lowden, M.D., Ph.D. * Patricia D. Murphy, Ph.D. * Patricia J. Numan, M.D. * Victoria O. Odesina, R.N., Sc.M., M.S. * Nancy Press, Ph.D. * Katherine A. Schneider, M.P.H. * David B. Singer * Steven Gutman, M.D., * Muin J. Khoury, M.D., Ph.D. * David Lanier, M.D. * Linda R.Lebovic * Jane S. Lin-Fu, M.D.…

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Zustand: New. pp. 204.

Buch. Zustand: Neu. Neuware - The Temple KeepThe Most Terrifying Secret in Human History Has been Hiding in Plain Sight for More Than Three Centuries. Until Now.In the fall of 2000, Noah Greaves arrives at the College of William & Mary in Virginia on a scholarship, carrying little more than a gift for mathematics, and a determination to escape the limits of small-town life. The mysterious Christopher Wren Building, the oldest college building in America, with its Georgian brick chambers and its deep roots in the founding of the nation, seems like the perfect pace to quietly reinvent himself. But when a Shakespeare professor notices Noah's uncanny ability to detect hidden patterns within centuries-old texts, his carefully ordinary semester unravels into something far stranger.Drawn into a secret world of cryptographers, historians, intelligence operatives, and occult seekers, Noah discovers that Williamsburg's famous colonial streetscape conceals more than history books admit. Beneath the restored facades of the Historic Area, beneath the taverns and the churchyards that once sheltered the founding of a republic, lie forgotten tunnels, sealed chambers, and a trail of encoded clues pointing towards a legendary vault -- one said to contain the greatest secret in human history.As rival factions close in, Noah and his enigmatic classmate Amanda find themselves in a deadly struggle connecting Sir Francis Bacon, coded messages hidden within Shakespeare's works, Thomas Jefferson, and a conspiracy that runs from Williamsburg's cobblestone streets to the deepest corridors of the Central Intelligence Agency. Each discovery raises questions about the history we thought we knew-- and the destiny we all must someday face.Blending historical mystery, espionage, horror, and speculative science fiction, The Temple Keep takes readers from candlelit college archives and the brick towers of Bruton Parish Church to a shocking revelation that challenges the nature of reality itself. Readers who loved The Da Vinci Code, The Secret History, National Treasure, and Dark Matter will find a relentless adventure where cryptography, hidden history, and cutting-edge science converge on one small American city where past, present, and future collide.Some secrets can change the world.One secret can end it.…

Zustand: New. pp. 204.

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Zustand: New. &Uumlber den AutorNeil A. Holtzman, M.D., M.P.H., is professor of pediatrics at the Johns Hopkins University School of Medicine. He holds joint appointments in Health Policy and Epidemiology at the Johns Hopkins School of Hyg.

Taschenbuch. Zustand: Neu. Neuware - Despite remarkable progress, much remains unknown about the risks and benefits of genetic testing. No effective interventions are yet available to improve the outcome of most inherited diseases; negative test results might not rule out future occurrence of disease, and positive test results do not necessarily mean the disease will inevitably develop. In view of this uncertainty, the Working Group on Ethical, Legal, and Social Implications of Human Genome Research at the National Institutes of Health and Department of Energy created the Task Force on Genetic Testing. Comprising representatives of fifteen major stakeholders in genetic testing and five government agencies involved with testing, the task force was charged with reviewing genetic testing in the United States and making recommendations to ensure the development of safe and effective genetic tests. In Promoting Safe and Effective Genetic Testing in the United States the members of this task force present the conclusions of their study. They begin by describing general principles involved in genetic testing, including informed consent, testing of children, confidentiality, and discrimination. They describe methods and policies to ensure the safety and effectiveness of new genetic tests, including criteria for developing tests and ways of ensuring compliance with those criteria. They then discuss how to ensure the quality of laboratories that perform genetic tests, including the role of laboratory personnel and methods of monitoring laboratory performance. They show how health care professionals outside the field of genetics can better understand the uses of genetic testing, and offer suggestions for changes in these professionals' education and training. Finally, they offer a look at testing for rare inherited genetic disorders.Members of the Task Force: Neil A. Holtzman, M.D., M.P.H. - Michael S. Watson, Ph.D., F.A.C.M.G. - Patricia A. Barr - David R. Cox, M.D., M.P.H. - Jessica G. Davis, M.D. - Stephen I. Goodman, M.D., M.Sc. - Wayne W. Grody, M.D., Ph.D. - Arthur L. Levin, M.D. - J. Alexander Lowden, M.D., Ph.D. - Patricia D. Murphy, Ph.D. - Patricia J. Numan, M.D. - Victoria O. Odesina, R.N., Sc.M., M.S. - Nancy Press, Ph.D. - Katherine A. Schneider, M.P.H. - David B. Singer - Steven Gutman, M.D., - Muin J. Khoury, M.D., Ph.D. - David Lanier, M.D. - Linda R. Lebovic - Jane S. Lin-Fu, M.D.…

Hardback. Zustand: New.

Paperback. Zustand: New. Despite remarkable progress, much remains unknown about the risks and benefits of genetic testing. No effective interventions are yet available to improve the outcome of most inherited diseases; negative test results might not rule out future occurrence of disease, and positive test results do not necessarily mean the disease will inevitably develop. In view of this uncertainty, the Working Group on Ethical, Legal, and Social Implications of Human Genome Research at the National Institutes of Health and Department of Energy created the Task Force on Genetic Testing. Comprising representatives of fifteen major stakeholders in genetic testing and five government agencies involved with testing, the task force was charged with reviewing genetic testing in the United States and making recommendations to ensure the development of safe and effective genetic tests. In Promoting Safe and Effective Genetic Testing in the United States the members of this task force present the conclusions of their study. They begin by describing general principles involved in genetic testing, including informed consent, testing of children, confidentiality, and discrimination.They describe methods and policies to ensure the safety and effectiveness of new genetic tests, including criteria for developing tests and ways of ensuring compliance with those criteria. They then discuss how to ensure the quality of laboratories that perform genetic tests, including the role of laboratory personnel and methods of monitoring laboratory performance. They show how health care professionals outside the field of genetics can better understand the uses of genetic testing, and offer suggestions for changes in these professionals' education and training. Finally, they offer a look at testing for rare inherited genetic disorders. Members of the Task Force: Neil A. Holtzman, M.D., M.P.H. * Michael S. Watson, Ph.D., F.A.C.M.G. * Patricia A. Barr * David R. Cox, M.D., M.P.H. * Jessica G. Davis, M.D. * Stephen I. Goodman, M.D., M.Sc. * Wayne W. Grody, M.D., Ph.D. * Arthur L. Levin, M.D. * J. Alexander Lowden, M.D., Ph.D. * Patricia D. Murphy, Ph.D. * Patricia J. Numan, M.D. * Victoria O. Odesina, R.N., Sc.M., M.S. * Nancy Press, Ph.D. * Katherine A. Schneider, M.P.H. * David B. Singer * Steven Gutman, M.D., * Muin J. Khoury, M.D., Ph.D. * David Lanier, M.D. * Linda R.Lebovic * Jane S. Lin-Fu, M.D.…

Hardcover. Zustand: new. Hardcover. The Temple KeepThe Most Terrifying Secret in Human History Has been Hiding in Plain Sight for More Than Three Centuries. Until Now.In the fall of 2000, Noah Greaves arrives at the College of William & Mary in Virginia on a scholarship, carrying little more than a gift for mathematics, and a determination to escape the limits of small-town life. The mysterious Christopher Wren Building, the oldest college building in America, with its Georgian brick chambers and its deep roots in the founding of the nation, seems like the perfect pace to quietly reinvent himself. But when a Shakespeare professor notices Noah's uncanny ability to detect hidden patterns within centuries-old texts, his carefully ordinary semester unravels into something far stranger.Drawn into a secret world of cryptographers, historians, intelligence operatives, and occult seekers, Noah discovers that Williamsburg's famous colonial streetscape conceals more than history books admit. Beneath the restored facades of the Historic Area, beneath the taverns and the churchyards that once sheltered the founding of a republic, lie forgotten tunnels, sealed chambers, and a trail of encoded clues pointing towards a legendary vault -- one said to contain the greatest secret in human history.As rival factions close in, Noah and his enigmatic classmate Amanda find themselves in a deadly struggle connecting Sir Francis Bacon, coded messages hidden within Shakespeare's works, Thomas Jefferson, and a conspiracy that runs from Williamsburg's cobblestone streets to the deepest corridors of the Central Intelligence Agency. Each discovery raises questions about the history we thought we knew-- and the destiny we all must someday face.Blending historical mystery, espionage, horror, and speculative science fiction, The Temple Keep takes readers from candlelit college archives and the brick towers of Bruton Parish Church to a shocking revelation that challenges the nature of reality itself. Readers who loved The Da Vinci Code, The Secret History, National Treasure, and Dark Matter will find a relentless adventure where cryptography, hidden history, and cutting-edge science converge on one small American city where past, present, and future collide.Some secrets can change the world.One secret can end it. A math prodigy at an ancient college uncovers a trail of ciphers hidden in Shakespeare's works, leading to the hunt for a legendary vault, a conspiracy at the heart of American history, and a secret that could shatter reality itself. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

HRD. Zustand: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

HRD. Zustand: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Hardcover. Zustand: new. Hardcover. The Temple KeepThe Most Terrifying Secret in Human History Has been Hiding in Plain Sight for More Than Three Centuries. Until Now.In the fall of 2000, Noah Greaves arrives at the College of William & Mary in Virginia on a scholarship, carrying little more than a gift for mathematics, and a determination to escape the limits of small-town life. The mysterious Christopher Wren Building, the oldest college building in America, with its Georgian brick chambers and its deep roots in the founding of the nation, seems like the perfect pace to quietly reinvent himself. But when a Shakespeare professor notices Noah's uncanny ability to detect hidden patterns within centuries-old texts, his carefully ordinary semester unravels into something far stranger.Drawn into a secret world of cryptographers, historians, intelligence operatives, and occult seekers, Noah discovers that Williamsburg's famous colonial streetscape conceals more than history books admit. Beneath the restored facades of the Historic Area, beneath the taverns and the churchyards that once sheltered the founding of a republic, lie forgotten tunnels, sealed chambers, and a trail of encoded clues pointing towards a legendary vault -- one said to contain the greatest secret in human history.As rival factions close in, Noah and his enigmatic classmate Amanda find themselves in a deadly struggle connecting Sir Francis Bacon, coded messages hidden within Shakespeare's works, Thomas Jefferson, and a conspiracy that runs from Williamsburg's cobblestone streets to the deepest corridors of the Central Intelligence Agency. Each discovery raises questions about the history we thought we knew-- and the destiny we all must someday face.Blending historical mystery, espionage, horror, and speculative science fiction, The Temple Keep takes readers from candlelit college archives and the brick towers of Bruton Parish Church to a shocking revelation that challenges the nature of reality itself. Readers who loved The Da Vinci Code, The Secret History, National Treasure, and Dark Matter will find a relentless adventure where cryptography, hidden history, and cutting-edge science converge on one small American city where past, present, and future collide.Some secrets can change the world.One secret can end it. A math prodigy at an ancient college uncovers a trail of ciphers hidden in Shakespeare's works, leading to the hunt for a legendary vault, a conspiracy at the heart of American history, and a secret that could shatter reality itself. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability.…

Hardcover. Zustand: new. Hardcover. The Temple KeepThe Most Terrifying Secret in Human History Has been Hiding in Plain Sight for More Than Three Centuries. Until Now.In the fall of 2000, Noah Greaves arrives at the College of William & Mary in Virginia on a scholarship, carrying little more than a gift for mathematics, and a determination to escape the limits of small-town life. The mysterious Christopher Wren Building, the oldest college building in America, with its Georgian brick chambers and its deep roots in the founding of the nation, seems like the perfect pace to quietly reinvent himself. But when a Shakespeare professor notices Noah's uncanny ability to detect hidden patterns within centuries-old texts, his carefully ordinary semester unravels into something far stranger.Drawn into a secret world of cryptographers, historians, intelligence operatives, and occult seekers, Noah discovers that Williamsburg's famous colonial streetscape conceals more than history books admit. Beneath the restored facades of the Historic Area, beneath the taverns and the churchyards that once sheltered the founding of a republic, lie forgotten tunnels, sealed chambers, and a trail of encoded clues pointing towards a legendary vault -- one said to contain the greatest secret in human history.As rival factions close in, Noah and his enigmatic classmate Amanda find themselves in a deadly struggle connecting Sir Francis Bacon, coded messages hidden within Shakespeare's works, Thomas Jefferson, and a conspiracy that runs from Williamsburg's cobblestone streets to the deepest corridors of the Central Intelligence Agency. Each discovery raises questions about the history we thought we knew-- and the destiny we all must someday face.Blending historical mystery, espionage, horror, and speculative science fiction, The Temple Keep takes readers from candlelit college archives and the brick towers of Bruton Parish Church to a shocking revelation that challenges the nature of reality itself. Readers who loved The Da Vinci Code, The Secret History, National Treasure, and Dark Matter will find a relentless adventure where cryptography, hidden history, and cutting-edge science converge on one small American city where past, present, and future collide.Some secrets can change the world.One secret can end it. A math prodigy at an ancient college uncovers a trail of ciphers hidden in Shakespeare's works, leading to the hunt for a legendary vault, a conspiracy at the heart of American history, and a secret that could shatter reality itself. This item is printed on demand. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.…