Jeffreys alec (3 Ergebnisse)
- Softcover
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Zustand: Bueno. Ediciones Akal,2008.Edición e introducción de Torsten Krude.24x17 cms,182 pags.Perfecto estado de conservación.REF 7959.

- Hardcover
- Signiert
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No Binding. Zustand: Very Good. 4"x 5" photo-card SIGNED by Dr. Alec Jeffreys. Sir Alec developed DNA fingerprint testing. SIGNED.
Verlag: institut national de la propietre industrielle Paris 1989
- Hardcover
- Erstausgabe
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Hardcover. Zustand: Very Good. 1st Edition. 3 patents First Editions. Overview of the Patents These three French patent filingsFR0002632656, FR000638171, and FR000002639651collectively describe: 1. Detection of Variable-Length Loci in DNA This refers to identifying Variable Number Tandem Repeats (VNTRs)regions of DNA that vary i…n length between individuals. VNTRs form the basis of DNA fingerprinting, allowing for unique genetic identification. 2. Nucleotide Sequences and Their Use The patents detail specific DNA probes used to bind to VNTR regions. These probes enable the visualization of genetic patterns via techniques like Southern blotting. 3. Evaluation of DNA Fragmentation Methods for assessing the integrity and fragmentation of DNA samplescritical for forensic and degraded specimen analysis. 4. Extension-Based Characterization of Genomic DNA Techniques for extending nucleotide sequences to analyze unknown DNA regions. This includes primer extension and probe hybridization strategies. 5. Diagnostic Kits The patents also cover commercial kits for implementing these methods in clinical and forensic settings. These kits standardize the process of DNA profiling, making it accessible to laboratories worldwide. Historical Significance These filings followed Jeffreys' September 1984 breakthrough at the University of Leicester, where he first observed the unique patterns in human DNA that led to the concept of genetic fingerprinting. By 1989, the technology had already been used to exonerate suspects, solve immigration disputes, and identify remains, prompting international patent protectionincluding in France.