Verlag: New York Academy of Sciences, USA, 1989
ISBN 10: 0897665392 ISBN 13: 9780897665391
Sprache: Englisch
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In den WarenkorbHardcover. Zustand: Fine. No Jacket. 0897665392. Unread Blue cloth hardcover, from closed pharmaceutical company library. 474 pages, illustrated, index. No Jacket as issued. Contents as new, unread, clean, tight and bright. Book.
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In den WarenkorbZustand: New. In.
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In den WarenkorbPaperback / softback. Zustand: New. New copy - Usually dispatched within 4 working days. 185.
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In den WarenkorbPaperback. Zustand: Brand New. 321 pages. 9.60x6.70x0.80 inches. In Stock.
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In den WarenkorbHardcover. Zustand: Very Good. 1st Edition. 532 pp., diagrams, bibliography, index. owner's name on FFEP. The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants. Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest as a coenzyme in mitochondrial energy metabolism and as an antioxidant and cell redox modulator. Mounting data regarding its potential health benefits demands an authoritative, single-source reference to codify current knowledge and guide future research. A state-of-the-science compilation, Lipoic Acid follows the history of this potent coenzyme and the latest discoveries regarding the chemistry, biological action, and significance in energy production, antioxidant activity, and health. The book is divided into three sections: · Section I: Discovery and Molecular Structure reviews the early studies leading to the discovery of alpha-lipoic acid and explains the molecular structure, biosynthesis, and the characterization of lipoic acid and its chemical derivatives. · Section II: Metabolic Aspects describes in detail the human pharmacokinetics of alpha-lipoic acid including the lipoic acid-derived dehydrogenase complexes and their roles in energy metabolism. It also explains antioxidant activity and redox modulation and how lipoic acid induces Phase II detoxification enzymes through activation of Nrf2-dependent gene expression. · Section III Clinical Aspects discusses enzyme deficiency disorders and the effects of lipoic acid on insulin. It defines lipoic acid influence on signaling pathways and AMP-activated kinase, and considers the therapeutic implications for treatment of metabolic syndromes and the improvement of mitochondrial function by lipoic acid supplementation.
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In den WarenkorbHardcover. Zustand: Good. 0824740629 Good; Hardcover; Moderate wear to the covers; Unblemished textblock edges; Pages are clean & unmarked; Good binding with a straight spine; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Light brown-green covers with title in white lettering; 2003, CRC Press; 600 pages; "Thiamine: Catalytic Mechanisms in Normal and Disease States (Oxidative Stress and Disease)," by Frank Jordan & Mulchand S. Patel.
Verlag: New York, New York: The New York Academy of Sciences,, 1989
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In den WarenkorbFirst edition. Foxing to the page edges, small crease to the upper front cover, else a near fine copy in illustrated wraps. Trade paperbound. Annals of the New York Academy of Sciences: Volume 573. 474 pages; subject index and index to contributors. Illustrated with figures and tables.
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In den WarenkorbZustand: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
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In den WarenkorbHRD. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
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