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In den WarenkorbPaperback. Zustand: Brand New. 85 pages. 8.75x6.00x0.25 inches. In Stock.
Sprache: Englisch
Verlag: National Academies Press, Washington, 2014
ISBN 10: 0309298210 ISBN 13: 9780309298216
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Paperback. Zustand: new. Paperback. Many drug developers have examined new strategies for creating efficiencies in their development processes, including the adoption of genomics-based approaches. Genomic data can identify new drug targets for both common and rare diseases, can predict which patients are likely to respond to a specific treatment, and has the potential to significantly reduce the cost of clinical trials by reducing the number of patients that must be enrolled in order to demonstrate safety and efficacy. A key component of the approval of targeted therapeutics is the ability to identify the population of patients who will benefit from treatment, and this has largely hinged on the co-development and co-submission to the FDA of a companion diagnostic test.The co-development process, or the development of the test and drug for the simultaneous submission to FDA, has led to a major alteration in the way that drugs are being developed, with traditionally separate entities-pharmaceutical and diagnostic companies-now working in close collaboration.Refining Processes for the Co-Development of Genome-Based Therapeutics and Companion Diagnostic Tests is the summary of a workshop held by the Roundtable on Translating Genomic-Based Research for Health on February 27, 2013 to examine and discuss challenges and potential solutions for the codevelopment of targeted therapeutics and companion molecular tests for the prediction of drug response. Prior to the workshop, key stakeholders, including laboratory and medical professional societies, were individually asked to provide possible solutions to resolve the concerns raised about co-development of companion diagnostic tests and therapies. Workshop speakers were charged with addressing these solutions in their presentations by providing insight on (1) whether the proposed solutions address the problems described, (2) whether there are other solutions to propose, and (3) what steps could be taken to effectively implement the proposed solutions. "Roundtable on Translating Genomic-Based Research for Health"--Cover. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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In den WarenkorbPAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
Sprache: Englisch
Verlag: National Academies Press 2014-04-06, 2014
ISBN 10: 0309298210 ISBN 13: 9780309298216
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Zustand: New. 2014. Illustrated. paperback. . . . . .
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In den WarenkorbPAP. Zustand: New. New Book. Shipped from UK. Established seller since 2000.
Sprache: Englisch
Verlag: National Academies Press, US, 2008
ISBN 10: 0309116767 ISBN 13: 9780309116763
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In den WarenkorbPaperback. Zustand: New. Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions.Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.
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In den WarenkorbZustand: New. In.
Sprache: Englisch
Verlag: National Academies Press, US, 2008
ISBN 10: 0309116767 ISBN 13: 9780309116763
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Paperback. Zustand: New. Until fairly recently, genetic information was used primarily in the diagnosis of relatively rare genetic diseases, such as cystic fibrosis and Huntington's Disease, but a transformation in the use of genetic and genomic information is underway. While many predictions have been made that genomics will transform medicine, to date few of these promising discoveries have resulted in actual applications in medicine and health. The Institute of Medicine's Roundtable on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address the following questions: 1. Are there different pathways by which new scientific findings move from the research setting into health care? 2. If so, what are the implications of those different pathways for genomics? 3. What can we learn from the translation of other new technologies as we seek to understand the translation of genome science into health care? Information obtained from the workshop was then used to further discussion and exploration of the answers to these questions. This book summarizes speaker presentations and discussions.Any conclusions reported should not be construed as reflecting a group consensus; rather they are the statements and opinions of presenters and participants.
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Zustand: New. The Institute of Medicine's Round table on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address questions such as are there different pathways by which new scientific findings move from the research setting into health care? This book summarizes speaker presentations and discussions. Editor(s): Hernandez, Lyla M. Num Pages: 116 pages, black & white tables, figures. BIC Classification: PSAK. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 8. Weight in Grams: 181. . 2008. Illustrated. paperback. . . . .
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In den WarenkorbZustand: New. pp. xv + 99 Illus.
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Zustand: New. The Institute of Medicine's Round table on Translating Genomic-Based Research for Health, established in 2007, held its first workshop to address questions such as are there different pathways by which new scientific findings move from the research setting into health care? This book summarizes speaker presentations and discussions. Editor(s): Hernandez, Lyla M. Num Pages: 116 pages, black & white tables, figures. BIC Classification: PSAK. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 8. Weight in Grams: 181. . 2008. Illustrated. paperback. . . . . Books ship from the US and Ireland.
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Zustand: New. Klappentextrnrn Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person s response to certain drugs, estimate the risk of developing Alzheimer s disease, and make other predictions ba.