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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This exceptional reference book provides comprehensive insights into the conditions and requirements necessary to establish an optimal and supportive transfusion practice. It focuses on enhancing the procurement process and manufacturing of blood products (components) in an evidence-based and cost-effective manner, specifically targeting the vital advancements needed in low and middle-income countries (LMICs), which are home to 84% of the global population.While this book does not delve into practical disciplinary guidelines, its emphasis lies on crucial topics. It explores the balance between restricted and liberal use of blood and blood components, the implementation and utilization of artificial intelligence (including machine learning and deep learning), and the integration of a digital footprint within clinical transfusion prescription and practice. Additionally, it addresses the significance of educating clinicians in transfusion medicine, considering the educational environment and curricular outcomes. By contributing to the development of appropriate clinical utilization of blood and blood components, the book highlights the importance of patient blood management, evidence-based decision-making, prescription practices, and bedside care delivered by well-informed professionals, including clinicians, nurses, and technologists. Furthermore, it underscores the significance of fostering a conducive climate and environment, nurturing knowledge economy, and implementing quality management practices.In its essence, this book serves as an invaluable source of knowledge to enhance transfusion medicine practices, refine clinical indication setting, and facilitate informed decision-making. By emphasizing patient comfort, welfare, and the reduction of unnecessary harm and risks, it aims to make a significant contribution to the field. Hematologists and professionals involved in transfusion medicine will find this book to be an indispensable reference that enhances their understanding and expertise.…

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Taschenbuch. Zustand: Neu. Neuware - In summary, the technical, scientific and medical aspects of transfusion me dicine continue to be critical. We all must find ways to provide a safer unit of blood and blood components. However, there must be a realization by all in volved in the profession that the management and administration aspects of transfusion medicine deserve equal attention, respect and support. Why It is very simple! Without all aspectsoftransfusion medicine working togetherfor the common good - care ofthe patient - we will all fail. References 1. Standards for Blood Banks and Transfusion Services, American Association of Blood Banks, 14th edition, Arlington, VA, USA, 1991. 2. Blood Assurance Act of 1979 (S.161O), Senator Richard S. Schweiker, United States Senate, Washington, DC, USA, July 31,1979. 3. Administrative Guidelines for Blood Banks, American Association of Blood Banks, Arlington, VA, 1989. 4. 'You're absolutely right: We goofed'. Howard Upton, Southwest Airlines Spirit, September 1991:24. 5. Administrative Manual, Volume II, American Association of Blood Banks, Arlington, VA, USA, 1987.…

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Taschenbuch. Zustand: Neu. Neuware - In transfusion medicine the scientific fundamentals of immunology have had a considerable clinical impact. Transfusion may suppress the immunity but some patients could suffer disadvantages including GvHD, alloimmunisation and possible cancer, where white cells (WBC) play pivotal roles in this phenomenon, presenting antigens and producing cytokines. A clinical application of this practice is LAK-cells targeted against cancer. MHC on the WBC may provide additional immunological modulations through series of secondary messengers. Thus reduction of WBC in the blood and bone marrow may be advantageous for patients. On the other hand, sharing a part of MHC or making the transplanted white cells anergic by storage may be even more advantageous for patients. CMV infection could mimic part of this MHC. UV radiation is effective in the inactivation of the WBC although filters are easy means for such removal. However, their accurate quantification requires flow cytometry that has considerable potential application in blood transfusions. Idiotypic antibody could play an important role in platelet theory. However, the potential infection risks in transfusion like HIV and HCV remain, but application of molecular biological methods like PCR or RT/PCR has great potentials in detection of infectious diseases, transplantation and genetic disorders. Immuno affinity purified concentrates, like factor IX and protein C, could reduce patients' immune functions, where in the future protein C could be derived from transgenic animals. Advances are sure to emerge through adoptive immunotherapy and gene therapies are exciting prospects when genes transferred into lymphocytes could be used to correct cell mediated immune deficiency, as in ADA.…

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - This exceptional reference book provides comprehensive insights into the conditions and requirements necessary to establish an optimal and supportive transfusion practice. It focuses on enhancing the procurement process and manufacturing of blood products (components) in an evidence-based and cost-effective manner, specifically targeting the vital advancements needed in low and middle-income countries (LMICs), which are home to 84% of the global population.While this book does not delve into practical disciplinary guidelines, its emphasis lies on crucial topics. It explores the balance between restricted and liberal use of blood and blood components, the implementation and utilization of artificial intelligence (including machine learning and deep learning), and the integration of a digital footprint within clinical transfusion prescription and practice. Additionally, it addresses the significance of educating clinicians in transfusion medicine, considering the educational environment and curricular outcomes. By contributing to the development of appropriate clinical utilization of blood and blood components, the book highlights the importance of patient blood management, evidence-based decision-making, prescription practices, and bedside care delivered by well-informed professionals, including clinicians, nurses, and technologists. Furthermore, it underscores the significance of fostering a conducive climate and environment, nurturing knowledge economy, and implementing quality management practices.In its essence, this book serves as an invaluable source of knowledge to enhance transfusion medicine practices, refine clinical indication setting, and facilitate informed decision-making. By emphasizing patient comfort, welfare, and the reduction of unnecessary harm and risks, it aims to make a significant contribution to the field. Hematologists and professionals involved in transfusion medicine will find this book to be an indispensable reference that enhances their understanding and expertise.…