Spandidos (41 Ergebnisse)
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Taschenbuch. Zustand: Neu. Neuware -since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking, cell proliferation, differentiation and cancer. These advan…ces led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting.
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Taschenbuch. Zustand: Neu. Neuware - since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking, cell proliferation, differentiation and cancer. These adva…nces led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting.
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Taschenbuch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Structure and Organization of the ras Gene Family, in Human.- Transcriptional Regulatory Sequences in the H-ras1 Gene.- Mutational Activation of Human ras Genes.- Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment.- Ras Mutati…ons in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy.- High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours.- Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers.- Human Thyroid Neoplasms Express ras p21 Protein at High Levels.- Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse.- Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors.- DNA Methylation of the Human Hras1 Gene.- Structure of the Drosophila ras2 Bidirectional Promoter.- The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells.- Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase.- The Function of the Mammalian ras Proteins.- Ras Proteins as Potential Activators of Protein Kinase C Function.- Novel Phosphorylation of ras p21 and Mutational Studies.- The Role of p21ras in Proliferative Signal Transduction.- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System.- Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene.- Regulation of Cell Death by ras and myc Oncogenes.- Ras-Induced Phenotypic Changes in Human Fibroblasts.- Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides.- Expression of ras, myc and fos Oncogenes During the DMSO-InducedDetransformation of a Colon Carcinoma Line (HT29).- The ras Oncogene and Myogenic Commitment and Differentiation.- Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc.- Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro.- Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction.- Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins.- Molecular Interactions of p21.- Ras-Transformed Cells Contain Microtubules Rich in Modified -Tubulin in Their Trailing Edges.- Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins.- Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene.- -Adrenoceptor is Required for Activation of Avian Erythrocyte GS by Guanine Nucleotides.- Expression of ras Oncogene in Xenopus laevis.- An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21.- Identification of a Protein Interacting with ras-p21- by Chemical Cross-Linking.- Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins.- Structural Investigations on the G-Binding Domain of p21.- Molecular Biology of GAP and its Interaction with Oncogenic ras p21.- The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells.
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Taschenbuch. Zustand: Neu. The Superfamily of ras-Related Genes | Demetrios A. Spandidos | Taschenbuch | NATO Science Series A: | 352 S. | Englisch | 2012 | Springer | EAN 9781468460209 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbie…ter: preigu.
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Taschenbuch. Zustand: Neu. ras Oncogenes | D. Spandidos | Taschenbuch | x | Englisch | 2013 | Springer | EAN 9781475712377 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Zustand: Sehr gut. Zustand: Sehr gut | Seiten: 318 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking,… cell proliferation, differentiation and cancer. These advances led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting. 352 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -since the earliest results on the linkage between ras activation and cell transformation appeared a vast amount of additional information has been generated which emphasizes the importance of ras-related genes in membrane trafficking,… cell proliferation, differentiation and cancer. These advances led to the development of new strategies for the diagnosis, prognosis and prevention of cancer. Ras-related genes appear to be central to the mechanism of transformation by other oncogenes and therefore constitute a focal point upon which attempts to intervene in the process of carcinogenesis will be concentrated. The present volume contains the contributions to the NATO Advanced Research Workshop on the 'The Superfamily of ras-Related Genes' held in Agia Pelagia, Heraklion, Crete, Greece, May 1991. At this meeting the leading researchers in this field carne together to discuss the most recent progress in analysis of biological function of the ras-related genes. As an organizer I feel that the Workshop was a success, and would like to thank all the participants and the contributors to this volume. I thank the NATO Scientific Affairs Division, Brussels, the Greek Ministry of Industry, Energy and Technology, the International Center for Cancer Research, the National Hellenic Research Foundation and the Medical School, University of Crete for sponsoring the Meeting. 352 pp. Englisch.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Structure and Organization of the ras Gene Family, in Human.- Transcriptional Regulatory Sequences in the H-ras1 Gene.- Mutational Activation of Human ras Genes.- Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatm…ent.- Ras Mutations in Primary Myelodysplasia and in Patients Following Cytotoxic Therapy.- High Frequency of ras Oncogene Activation in Benign and Malignant Human Thyroid Tumours.- Alterations of C-Ha-ras Gene are Associated with c-myc Activation in Human Cervical Cancers.- Human Thyroid Neoplasms Express ras p21 Protein at High Levels.- Detection of Mutations in the H-ras Proto-Oncogene in Liver Tumours of the CF1 Mouse.- Analysis of Hras1-Associated Polymorphisms and Segregation of Taq1-Defined Alleles in Different Human Tumors.- DNA Methylation of the Human Hras1 Gene.- Structure of the Drosophila ras2 Bidirectional Promoter.- The rap Proteins : GTP Binding Proteins Related to p21 ras with a Possible Reversion Effect on ras Transformed Cells.- Suppression of Temperature-Sensitive RAS in S.cerevisiae by a Putative Protein Kinase.- The Function of the Mammalian ras Proteins.- Ras Proteins as Potential Activators of Protein Kinase C Function.- Novel Phosphorylation of ras p21 and Mutational Studies.- The Role of p21ras in Proliferative Signal Transduction.- Characterization of ras Proteins Produced at High Levels in the Baculovirus Expression System.- Phenotypic and Cytogenetic Alterations in Human Skin Keratinocytes after Transfection with the Cellular Harvey-ras (c-Ha-ras) Oncogene.- Regulation of Cell Death by ras and myc Oncogenes.- Ras-Induced Phenotypic Changes in Human Fibroblasts.- Suppression of ras Oncogene Expression Using Sequence Specific Oligodeoxynucleotides.- Expression of ras, myc and fos Oncogenes During the DMSO-Induced Detransformation of a Colon Carcinoma Line (HT29).- The ras Oncogene and Myogenic Commitment and Differentiation.- Tumorigenic Conversion of in vivo Differentiation Competent Mammary Cells by Introduction and Expression of ras or mil(raf) but not myc.- Activation of the Human c-Ha-ras-1 Gene by Chemical Carcinogens in vitro.- Activation of ras Oncogenes During Colonic Carcinogenesis: Detection by the Polymerase Chain Reaction.- Post-Translational Modification of ras Proteins: Palmitoylation and Phosphorylation of Yeast ras Proteins.- Molecular Interactions of p21.- Ras-Transformed Cells Contain Microtubules Rich in Modified -Tubulin in Their Trailing Edges.- Glutathione S-Transferase/ras Fusion Protein: A Tool for Affinity Chromatography of ras Associated Proteins.- Aristolochic Acid I Induced Tumors in Wistar Rats Contain Activating Mutations in Codon 61 of the H-ras Protooncogene.- -Adrenoceptor is Required for Activation of Avian Erythrocyte GS by Guanine Nucleotides.- Expression of ras Oncogene in Xenopus laevis.- An Appraisal of Four Monoclonal Antibodies Used in the Immunohistochemical Detection of ras p21.- Identification of a Protein Interacting with ras-p21- by Chemical Cross-Linking.- Isolation and Partial Characterization of a New Gene (br1) Belonging to the Superfamily of the Small GTP-Binding Proteins.- Structural Investigations on the G-Binding Domain of p21.- Molecular Biology of GAP and its Interaction with Oncogenic ras p21.- The Cooperation between Viral ras Genes and Different Immortalizing Genes Induces the Transformation of Rat Thyroid Epithelial Cells. 336 pp. Englisch.
