vijayakumar govindaraj (13 Ergebnisse)

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Taschenbuch. Zustand: Neu. Neuware -The aim of the study was to determine whether estrogen improves the impaired cardiac glucose uptake in cardiac hypertrophy which could provide a mechanism to explain the prevention of cardiac hypertrophy by estrogen using spontaneously hypertensive rats (SHR). To examine this ovariectomized (OVX) and ovariectomized estradiol-implanted (OVX-E2) SHR rats were analyzed. At the end of the treatment the degree of cardiac hypertrohy, serum hormone levels, cardiac glucose uptake by FDG-PET and GLUT4 localization and expression, and cardiac hexokinase activity were analyzed. Results revealed that estrogen substitution inhibits uterine atrophy and cardiac hypertrophy in OVX+E2 group compared to OVX. PET analysis showed a significant increase in myocardial glucose uptake in OVX+E2 compared to OVX group. Confocal microscopy and western blotting demonstrated higher GLUT4 translocation on plasma membrane in E2 treated rat heart. Micro-array gene expression analysis showed differentially expressed genes that are involved in the mTOR signaling pathway which is known to be activated during cardiac hypertrophy.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 84 pp. Englisch.

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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vijayakumar RamasamyDr.Ramasamy Vijayakumar is working as Assistant Professor, at Department of Microbiology, Bharathidasan University College, Peramabalur, India. His current research focus is on actinobacteria, Mushroom, Marine Mic.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vijayakumar RamasamyDr. Ramasamy Vijayakumar arbeitet als Assistenzprofessor in der Abteilung fuer Mikrobiologie am Bharathidasan University College, Peramabalur, Indien. Sein derzeitiger Forschungsschwerpunkt liegt auf Aktinobakterie.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Govindaraj VijayakumarDr. Vijayakumar Govindaraj obtained his Ph.D degree in Biology from University of Wuerzburg, Germany. He is currently a Postdoctoral Fellow at Indian Institute of Science, Bangalore, India. His main focus of re.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of the study was to determine whether estrogen improves the impaired cardiac glucose uptake in cardiac hypertrophy which could provide a mechanism to explain the prevention of cardiac hypertrophy by estrogen using spontaneously hypertensive rats (SHR). To examine this ovariectomized (OVX) and ovariectomized estradiol-implanted (OVX-E2) SHR rats were analyzed. At the end of the treatment the degree of cardiac hypertrohy, serum hormone levels, cardiac glucose uptake by FDG-PET and GLUT4 localization and expression, and cardiac hexokinase activity were analyzed. Results revealed that estrogen substitution inhibits uterine atrophy and cardiac hypertrophy in OVX+E2 group compared to OVX. PET analysis showed a significant increase in myocardial glucose uptake in OVX+E2 compared to OVX group. Confocal microscopy and western blotting demonstrated higher GLUT4 translocation on plasma membrane in E2 treated rat heart. Micro-array gene expression analysis showed differentially expressed genes that are involved in the mTOR signaling pathway which is known to be activated during cardiac hypertrophy. 84 pp. Englisch.

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The aim of the study was to determine whether estrogen improves the impaired cardiac glucose uptake in cardiac hypertrophy which could provide a mechanism to explain the prevention of cardiac hypertrophy by estrogen using spontaneously hypertensive rats (SHR). To examine this ovariectomized (OVX) and ovariectomized estradiol-implanted (OVX-E2) SHR rats were analyzed. At the end of the treatment the degree of cardiac hypertrohy, serum hormone levels, cardiac glucose uptake by FDG-PET and GLUT4 localization and expression, and cardiac hexokinase activity were analyzed. Results revealed that estrogen substitution inhibits uterine atrophy and cardiac hypertrophy in OVX+E2 group compared to OVX. PET analysis showed a significant increase in myocardial glucose uptake in OVX+E2 compared to OVX group. Confocal microscopy and western blotting demonstrated higher GLUT4 translocation on plasma membrane in E2 treated rat heart. Micro-array gene expression analysis showed differentially expressed genes that are involved in the mTOR signaling pathway which is known to be activated during cardiac hypertrophy.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Vijayakumar RamasamyIl dottor Ramasamy Vijayakumar lavora come professore assistente presso il Dipartimento di Microbiologia del Bharathidasan University College, Peramabalur, India. La sua ricerca si concentra attualmente su actinob.

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