ISBN: 9781461406129 - natural killer t cells: balancing the regulation of tumor immunity (cancer drug discovery and development) (13 Ergebnisse)

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Zustand: New. 2011. Hardcover. . . . . .

Zustand: New. pp. 220 Index.

Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Natural killer T (NKT) cells are CD1d-restricted T cells that respond to lipid, not protein, antigens presented by CD1d, which is a non-classical MHC class I-like molecule. This relatively small but pivotal T cell population bridges the gap between innate and adaptive immunity by rapidly produce large amounts of many kinds of cytokines and by providing the T cell arm of the adaptive immune system a mechanism to detect lipid antigens. NKT cells also have both regulatory and effector functions and have been shown to play critical roles in the regulation of immune responses in many disease settings including cancer. Stimulating the protective functions of NKT cells while inhibiting the negative regulatory activity shows promise for the therapy of cancer and several approaches are in clinical trials.This book reviews what we have learned about NKT cells during last two decades through functional studies in the context of tumor immunology, including clinical trials of NKT cell targeted therapy. This knowledge should also be informative to understand the role of this underappreciated T cell population in many other fields outside of tumor immunology.…

Hardcover. Zustand: Brand New. 1st edition. 205 pages. 9.00x6.25x0.50 inches. In Stock.

Zustand: New. 2011. Hardcover. . . . . . Books ship from the US and Ireland.

Zustand: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.

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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Natural killer T (NKT) cells are CD1d-restricted T cells that respond to lipid, not protein, antigens presented by CD1d, which is a non-classical MHC class I-like molecule. This relatively small but pivotal T cell population bridges the gap between innate and adaptive immunity by rapidly produce large amounts of many kinds of cytokines and by providing the T cell arm of the adaptive immune system a mechanism to detect lipid antigens. NKT cells also have both regulatory and effector functions and have been shown to play critical roles in the regulation of immune responses in many disease settings including cancer. Stimulating the protective functions of NKT cells while inhibiting the negative regulatory activity shows promise for the therapy of cancer and several approaches are in clinical trials.This book reviews what we have learned about NKT cells during last two decades through functional studies in the context of tumor immunology, including clinical trials of NKT cell targeted therapy. This knowledge should also be informative to understand the role of this underappreciated T cell population in many other fields outside of tumor immunology. 220 pp. Englisch.…

Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Natural killer T (NKT) cells discussed in this book are CD1d-restricted T cellsOverview of structures and functions of glycolipid antigensExplains roles of NKT cells in human lymphoma patientsThis book will cover primary roles of NK.…

Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book will cover primary roles of NKT cells in immunity to cancer, in both mouse tumor models and cancer patients. There are several chapters describing general aspects of NKT cells.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 220 pp. Englisch. …

Zustand: New. Print on Demand pp. 220.

Zustand: New. PRINT ON DEMAND pp. 220.