ISBN: 9783330014213 - characterization of peroxynitrite modified glycated dna (5 Ergebnisse)

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  • Sprache: Englisch

    Verlag: LAP LAMBERT Academic Publishing, 2016

    3330014210 / 9783330014213

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    Paperback. Zustand: Brand New. 68 pages. 8.66x5.91x0.16 inches. In Stock.

  • Sprache: Englisch

    Verlag: LAP Lambert Academic Publishing Dez 2016, 2016

    3330014210 / 9783330014213

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    Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Glycation is the non-enzymatic addition or insertion of sugar molecules into DNA, protein and lipids that occur in biological molecules. The glycation of DNA give rise to characteristic nucleotide adducts, some of which have been found to increase in oxidative stress . The glycation causes damage to DNA which is associated with mutagenesis, carcinogenesis and is also considered to be a pathogenic factor for Diabetes mellitus. Improved understanding of DNA glycation may give guidance on decreasing the risk of tumor associated with dietary factors.Peroxynitrite is a potent initiator of DNA strand breakage which is an obligatory stimulus for activation of nuclear enzyme, poly-ADP ribosyl synthase or polymerase (PARP) excess activation of PARP can kill cell by depleting NAD+ and energy production, and this may be one of the mechanism by which cells with excess DNA damage are eliminated ( which undergoes necrosis or apoptosis). 68 pp. Englisch.…

  • Sprache: Englisch

    Verlag: LAP LAMBERT Academic Publishing, 2016

    3330014210 / 9783330014213

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    Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Glycation is the non-enzymatic addition or insertion of sugar molecules into DNA, protein and lipids that occur in biological molecules. The glycation of DNA give rise to characteristic nucleotide adducts, some of which have been found to increase in oxidative stress . The glycation causes damage to DNA which is associated with mutagenesis, carcinogenesis and is also considered to be a pathogenic factor for Diabetes mellitus. Improved understanding of DNA glycation may give guidance on decreasing the risk of tumor associated with dietary factors.Peroxynitrite is a potent initiator of DNA strand breakage which is an obligatory stimulus for activation of nuclear enzyme, poly-ADP ribosyl synthase or polymerase (PARP) excess activation of PARP can kill cell by depleting NAD+ and energy production, and this may be one of the mechanism by which cells with excess DNA damage are eliminated ( which undergoes necrosis or apoptosis). …

  • Sprache: Englisch

    Verlag: LAP LAMBERT Academic Publishing, 2016

    3330014210 / 9783330014213

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    Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Ahmad RizwanDr. Rizwan Ahmad is working as Dean Academics and Head,Biochemistry Department, Uttaranchal (PG) College of Biomedical Sciences and Hospital, Dehradun, India. Dr. Ahmad did his M.Phil. and Ph.D. in Biochemistry from Facul. …

  • Sprache: Englisch

    Verlag: LAP LAMBERT Academic Publishing Dez 2016, 2016

    3330014210 / 9783330014213

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    Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Glycation is the non-enzymatic addition or insertion of sugar molecules into DNA, protein and lipids that occur in biological molecules. The glycation of DNA give rise to characteristic nucleotide adducts, some of which have been found to increase in oxidative stress . The glycation causes damage to DNA which is associated with mutagenesis, carcinogenesis and is also considered to be a pathogenic factor for Diabetes mellitus. Improved understanding of DNA glycation may give guidance on decreasing the risk of tumor associated with dietary factors.Peroxynitrite is a potent initiator of DNA strand breakage which is an obligatory stimulus for activation of nuclear enzyme, poly-ADP ribosyl synthase or polymerase (PARP) excess activation of PARP can kill cell by depleting NAD+ and energy production, and this may be one of the mechanism by which cells with excess DNA damage are eliminated ( which undergoes necrosis or apoptosis).VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 68 pp. Englisch. …