9783540297130 - current concepts in autoimmunity and chronic inflammation (current topics in microbiology and immunology, 305, band 305) (9 Ergebnisse)
Sprache: Englisch
Verlag: Springer, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
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Sprache: Englisch
Verlag: Springer, 2006
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Sprache: Englisch
Verlag: Springer, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
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Sprache: Englisch
Verlag: Springer, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of 'horror aut…otoxicus' is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality.
Sprache: Englisch
Verlag: Springer, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Sprache: Englisch
Verlag: Springer Verlag, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Hardcover. Zustand: Brand New. 1st edition. 282 pages. 9.50x6.25x0.75 inches. In Stock.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Discusses the complex ethiopathologies of autoimmune diseasesExplores the broad variety of cell types and genes involvedShows how initiating factors in autoimmune disease can possibly be distinct from those that drive t…he chro.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg Apr 2006, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principl…e of 'horror autotoxicus' is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality. 296 pp. Englisch.
Sprache: Englisch
Verlag: Springer Berlin Heidelberg, Springer Berlin Heidelberg Apr 2006, 2006
Serie: Buch 20 von 322 - Current Topics in Microbiology and Immunology
- Hardcover
- Print-on-Demand
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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The immune system has been known to be capable of distinguishing self from non-self since the pioneering work of Paul Erhlich more than a century ago. Originally described in experiments studying blood transfusion comp- ibility, the principle of… ¿horror autotoxicus¿ is still valid, although today the phenomenon is usually described in terms of tolerance or ignorance. A great deal has been learned about the various processes preventing self-reactivity normally. These include processes that operate during immune cell ontogeny and subsequently on reactivity of mature lymphocytes in the periphery. They encompass mechanisms that are intrinsic to potentially reactive lymphocytes and can result in central or peripheral deletion or the alteration of functional potential. In addition, there are in uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf cking patterns involved in generating productive immune interactions. It is clear that the immune system devotes a considerable effort to the avoidance of the development of potentially pathogenic self-reactivity. Despite this, the development of self-reactivity is relatively common. - though the development of autoimmune disease is less frequent, autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, systemic lupus e- thematosus, psoriasis, thyroiditis, and myasthenia gravis, are all too common, and can cause considerable morbidity and even mortality. 296 pp. Englisch.
