Isbn: 9783540624592 - preparative chromatography techniques: applications in natural product isolation (14 Ergebnisse)

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Zustand: Gut. Zustand: Gut | Seiten: 260 | Sprache: Englisch | Produktart: Bücher | Over the past few years, increasing attention has been paid to the search for bioactive compounds from natural sources. The success of plant-derived products such as paclitaxel (Taxol) in tumor therapy or artemisinin in the treatment of malaria has provided the impetus for the introduction of numerous research programmes, especially in Industry. A great deal of effort is being expended in the generation of novel lead molecules of vegetable, marine and microbial origin by the use of high throughput screening protocols. When interesting hits are found, it is essen tial to have methods available for the rapid isolation of target compounds. For this reason, both industry and academia need efficient preparative chromatographic separation techniques and experience in their application. Purified natural products are required for complete spectro scopic identification and full characterization of new compo unds, for biological testing and for the supply of pharmaceuti cals, standards, and starting materials for synthetic work. Obtaining pure products from an extract can be a very long, te dious and expensive undertaking, involving many steps. Sometimes only minute amounts of the desired compounds are at hand and these entities may be labile. Thus it is an advantage to have access to as many different methods as possible in order to aid the isolation process. Although a certain amount of trial and error may be involved, nowadays there is the possibility of devising suitable rapid separation schemes by a judicious choice of the different techniques available.…

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Buch. Zustand: Neu. Druck auf Anfrage Neuware - Printed after ordering - Over the past few years, increasing attention has been paid to the search for bioactive compounds from natural sources. The success of plant-derived products such as paclitaxel (Taxol) in tumor therapy or artemisinin in the treatment of malaria has provided the impetus for the introduction of numerous research programmes, especially in Industry. A great deal of effort is being expended in the generation of novel lead molecules of vegetable, marine and microbial origin by the use of high throughput screening protocols. When interesting hits are found, it is essen tial to have methods available for the rapid isolation of target compounds. For this reason, both industry and academia need efficient preparative chromatographic separation techniques and experience in their application. Purified natural products are required for complete spectro scopic identification and full characterization of new compo unds, for biological testing and for the supply of pharmaceuti cals, standards, and starting materials for synthetic work. Obtaining pure products from an extract can be a very long, te dious and expensive undertaking, involving many steps. Sometimes only minute amounts of the desired compounds are at hand and these entities may be labile. Thus it is an advantage to have access to as many different methods as possible in order to aid the isolation process. Although a certain amount of trial and error may be involved, nowadays there is the possibility of devising suitable rapid separation schemes by a judicious choice of the different techniques available.; This book describes modern preparative chromatography techniques and their application in the separation of natural products, synthetic intermediates, metabolites, macromolecules, and biologically active substances, e.g. new lead compounds from microorganisms and both marine and terrestrial higher organisms. The authors focus their book on the applications and aim to provide the reader with a rapid idea of how to obtain milligram or gram quantities of pure constituents from complex mixtures with minimum effort.Among others different pressure LC methods, including preparative HPLC and medium-pressure LC are treated and new all-liquid techniques, e.g. centrifugal partition chromatography, are discussed in detail. Descriptions of apparatus and operation procedures together with numerous examples of actual separations - often widely scattered in literature - are provided. This completely revised second edition has been enlarged by chapters on macromolecule and enantiomer separation and on preparative GC.…

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Zustand: New. pp. 260 2nd Completely Revised & Enlarged Edition.

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Gebunden. Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. State-of-the-art and practice-oriented approach no competing book on the marketState-of-the-art and practice-oriented approachno competing book on the marketOver the past few years, increasing attention has been paid to the search fo.…

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Buch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book describes modern preparative chromatography techniques and their application in the separation of natural products, synthetic intermediates, metabolites, macromolecules, and biologically active substances, e.g. new lead compounds from microorganisms and both marine and terrestrial higher organisms. The authors focus their book on the applications and aim to provide the reader with a rapid idea of how to obtain milligram or gram quantities of pure constituents from complex mixtures with minimum effort.Among others different pressure LC methods, including preparative HPLC and medium-pressure LC are treated and new all-liquid techniques, e.g. centrifugal partition chromatography, are discussed in detail. Descriptions of apparatus and operation procedures together with numerous examples of actual separations - often widely scattered in literature - are provided. This completely revised second edition has been enlarged by chapters on macromolecule and enantiomer separation and on preparative GC. 260 pp. Englisch.…

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Buch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -With the increasing interest in the discovery of new biologically active compounds there is a constant need to separate complex mixtures effectively, rapidly, and inexpensively. This book aims at providing the reader with a rapid idea how to solve a respective problem and describes apparatus, operation procedures and numerous applications in detail and with the expertise of experienced practitioners.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 260 pp. Englisch.…

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Zustand: New. Print on Demand pp. 260 52:B&W 6.14 x 9.21in or 234 x 156mm (Royal 8vo) Case Laminate on White w/Gloss Lam.

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Zustand: New. PRINT ON DEMAND pp. 260.