ISBN: 9786139822515 - new biomarkers in evaluating interactions of two cytotoxic agents (7 Ergebnisse)

Taschenbuch. Zustand: Neu. New Biomarkers in Evaluating Interactions of Two Cytotoxic Agents | Ola El-Habit (u. a.) | Taschenbuch | 168 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786139822515 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Paperback. Zustand: Brand New. 168 pages. 8.66x5.91x0.38 inches. In Stock.

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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We tested the cytotoxicity; gene expression of miR146a and let7a; oxidative stress and antioxidant enzymes activity and the histopathological changes in liver tissues of rat. Two dose of NaAsO2 (5mg/kg) and CdCl2 (1 mg/kg) were administered by oral gavage and intraperitoneally injection, respectively, for 14 and 28 consecutive days. We evaluated the possible interaction between cadmium and arsenate. Very few reports have addressed the possible interaction of chronic concontaminant exposures to mixtures of these metals in both occupational and environmental settings. Metal-metal interaction may lead to severe adverse effects by enhancing the effects of both metals through some additive or synergistic actions. The study concluded that there are a close relationship of high epigenetic changes as deregulation of both (miR146a) and (miRlet7a) due to the toxic effect of sodium arsenite and cadmium chloride alone or in combination and a major changes in hepatic tissues that may lead to cell transformations from normal to becoming cancerous cells. 168 pp. Englisch. …

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: El-Habit OlaOla El-Habit Prof. of Genetics, Faculty of Science, Zoology and Entomology Department, Helwan University. Ex. Head of Zoology and Entomology Department, Helwan University. Prof. of Genetics, Zoology Department, King Saud .…

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - We tested the cytotoxicity; gene expression of miR146a and let7a; oxidative stress and antioxidant enzymes activity and the histopathological changes in liver tissues of rat. Two dose of NaAsO2 (5mg/kg) and CdCl2 (1 mg/kg) were administered by oral gavage and intraperitoneally injection, respectively, for 14 and 28 consecutive days. We evaluated the possible interaction between cadmium and arsenate. Very few reports have addressed the possible interaction of chronic concontaminant exposures to mixtures of these metals in both occupational and environmental settings. Metal-metal interaction may lead to severe adverse effects by enhancing the effects of both metals through some additive or synergistic actions. The study concluded that there are a close relationship of high epigenetic changes as deregulation of both (miR146a) and (miRlet7a) due to the toxic effect of sodium arsenite and cadmium chloride alone or in combination and a major changes in hepatic tissues that may lead to cell transformations from normal to becoming cancerous cells.…

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -We tested the cytotoxicity; gene expression of miR146a and let7a; oxidative stress and antioxidant enzymes activity and the histopathological changes in liver tissues of rat. Two dose of NaAsO2 (5mg/kg) and CdCl2 (1 mg/kg) were administered by oral gavage and intraperitoneally injection, respectively, for 14 and 28 consecutive days. We evaluated the possible interaction between cadmium and arsenate. Very few reports have addressed the possible interaction of chronic concontaminant exposures to mixtures of these metals in both occupational and environmental settings. Metal-metal interaction may lead to severe adverse effects by enhancing the effects of both metals through some additive or synergistic actions. The study concluded that there are a close relationship of high epigenetic changes as deregulation of both (miR146a) and (miRlet7a) due to the toxic effect of sodium arsenite and cadmium chloride alone or in combination and a major changes in hepatic tissues that may lead to cell transformations from normal to becoming cancerous cells.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 168 pp. Englisch.…