9786139936663 - Dementia Confidential: Aiming for Normal Aging, versus Dementia von D'Arrigo, Joseph (6 Ergebnisse)

Paperback. Zustand: Brand New. 84 pages. 8.66x5.91x0.19 inches. In Stock.

Taschenbuch. Zustand: Neu. Dementia Confidential: Aiming for Normal Aging, versus Dementia | Joseph D'Arrigo | Taschenbuch | 84 S. | Englisch | 2018 | LAP LAMBERT Academic Publishing | EAN 9786139936663 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.

Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A frequent coexistence of cerebrovascular pathology and Alzheimer's disease pathology has been observed over past decades. Accordingly, there is much documentary evidence indicating that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, obesity, diabetes, smoking, hypertension, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. This book describes a multitasking combination therapeutic (i.e., biomimetic lipid nanocarrier for several drugs) which crosses the blood-brain barrier, and readily binds to populations of cell-surface scavenger receptors (mainly SR-BI) simultaneously in brain tissue. These same receptor classes have been extensively reported to occur prominently on various Alzheimer's-related cell types. Hence, this multitasking (targeted drug-delivery) therapeutic may also display greater effectiveness at different stages of Alzheimer's disease. Such a multitasking therapeutic approach could be especially useful to pharmaceutical researchers, graduate students and medical professionals by representing a promising way to treat, delay, or even prevent the disease in the future. 84 pp. Englisch.

Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: D Arrigo JosephDr D Arrigo has a BA in Chemistry (1967, Queens College, NY, NY) two years of medical school (1967-69, U of Wisconsin) and a PhD in Neuroscience (1972, UCLA). He has held medical faculty positions at U of Utah (1973-.

Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -A frequent coexistence of cerebrovascular pathology and Alzheimer's disease pathology has been observed over past decades. Accordingly, there is much documentary evidence indicating that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, obesity, diabetes, smoking, hypertension, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. This book describes a multitasking combination therapeutic (i.e., biomimetic lipid nanocarrier for several drugs) which crosses the blood-brain barrier, and readily binds to populations of cell-surface scavenger receptors (mainly SR-BI) simultaneously in brain tissue. These same receptor classes have been extensively reported to occur prominently on various Alzheimer's-related cell types. Hence, this multitasking (targeted drug-delivery) therapeutic may also display greater effectiveness at different stages of Alzheimer's disease. Such a multitasking therapeutic approach could be especially useful to pharmaceutical researchers, graduate students and medical professionals by representing a promising way to treat, delay, or even prevent the disease in the future.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 84 pp. Englisch.

Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - A frequent coexistence of cerebrovascular pathology and Alzheimer's disease pathology has been observed over past decades. Accordingly, there is much documentary evidence indicating that microvascular endothelial dysfunction, due to cerebrovascular risk factors (e.g., atherosclerosis, obesity, diabetes, smoking, hypertension, aging), precedes cognitive decline in Alzheimer's disease and contributes to its pathogenesis. This book describes a multitasking combination therapeutic (i.e., biomimetic lipid nanocarrier for several drugs) which crosses the blood-brain barrier, and readily binds to populations of cell-surface scavenger receptors (mainly SR-BI) simultaneously in brain tissue. These same receptor classes have been extensively reported to occur prominently on various Alzheimer's-related cell types. Hence, this multitasking (targeted drug-delivery) therapeutic may also display greater effectiveness at different stages of Alzheimer's disease. Such a multitasking therapeutic approach could be especially useful to pharmaceutical researchers, graduate students and medical professionals by representing a promising way to treat, delay, or even prevent the disease in the future.