9786200325891 - design and development of mucoadhesive microspheres: mucoadhesive microspheres von shinde, anilkumar; more, harinath (8 Ergebnisse)
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Taschenbuch. Zustand: Neu. DESIGN AND DEVELOPMENT OF MUCOADHESIVE MICROSPHERES | MUCOADHESIVE MICROSPHERES | Anilkumar Shinde (u. a.) | Taschenbuch | Englisch | 2022 | LAP LAMBERT Academic Publishing | EAN 9786200325891 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]p…reigu[dot]de | Anbieter: preigu.
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Taschenbuch. Zustand: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biodegradable microspheres are one of the most useful devices to deliver materials in an effective, prolonged and safe manner. Mucoadhesion is a novel area of interest in the design of drug delivery systems to maintain the dosage form… at the site of action or absorption and to facilitate intimate contact of the dosage form with underlying absorption surface to improve and enhance bioavailability. Repaglinide is a meglitinide analogue used as oral hypoglycaemic drug and having very low t1/2 (~ 1hr.), 56% bioavailability. It is totally absorbed from GIT, so it is the need to increase its transit time, by formulating with HPMC K4M, sodium alginate and Carbopol 934 P. Sodium alginate microspheres for an anti diabetic drug, repaglinide, were prepared by ionic-gelation method and investigated for its various physicochemical and release properties. Incorporation of HPMC K4M and Carbopol 934 P in the formulations affected the mucoadhesion, % water absorption, shape and release pattern of the formulations. Drug release from the microspheres followed peppas order kinetics. The prepared batches were found to sustained the release of the drug for 12 hours. 56 pp. Englisch.
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Zustand: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Biodegradable microspheres are one of the most useful devices to deliver materials in an effective, prolonged and safe manner. Mucoadhesion is a novel area of interest in the design of drug delivery systems to maintain…the dosage form at the site of action .
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Taschenbuch. Zustand: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biodegradable microspheres are one of the most useful devices to deliver materials in an effective, prolonged and safe manner. Mucoadhesion is a novel area of interest in the design of drug delivery systems to maintain the dosage form at…the site of action or absorption and to facilitate intimate contact of the dosage form with underlying absorption surface to improve and enhance bioavailability. Repaglinide is a meglitinide analogue used as oral hypoglycaemic drug and having very low t1/2 (~ 1hr.), 56% bioavailability. It is totally absorbed from GIT, so it is the need to increase its transit time, by formulating with HPMC K4M, sodium alginate and Carbopol 934 P. Sodium alginate microspheres for an anti diabetic drug, repaglinide, were prepared by ionic-gelation method and investigated for its various physicochemical and release properties. Incorporation of HPMC K4M and Carbopol 934 P in the formulations affected the mucoadhesion, % water absorption, shape and release pattern of the formulations. Drug release from the microspheres followed peppas order kinetics. The prepared batches were found to sustained the release of the drug for 12 hours.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 56 pp. Englisch.
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Taschenbuch. Zustand: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Biodegradable microspheres are one of the most useful devices to deliver materials in an effective, prolonged and safe manner. Mucoadhesion is a novel area of interest in the design of drug delivery systems to maintain the dosage form at t…he site of action or absorption and to facilitate intimate contact of the dosage form with underlying absorption surface to improve and enhance bioavailability. Repaglinide is a meglitinide analogue used as oral hypoglycaemic drug and having very low t1/2 (~ 1hr.), 56% bioavailability. It is totally absorbed from GIT, so it is the need to increase its transit time, by formulating with HPMC K4M, sodium alginate and Carbopol 934 P. Sodium alginate microspheres for an anti diabetic drug, repaglinide, were prepared by ionic-gelation method and investigated for its various physicochemical and release properties. Incorporation of HPMC K4M and Carbopol 934 P in the formulations affected the mucoadhesion, % water absorption, shape and release pattern of the formulations. Drug release from the microspheres followed peppas order kinetics. The prepared batches were found to sustained the release of the drug for 12 hours.
